Strategy: All Of Bitcoin’s Volatility, None Of The Utility (NASDAQ:MSTR) Seeking Alpha
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LIVE: Fed Rate Cut Decision — Bitcoin & Crypto Market Reaction Updates, September 17 – Cryptonews
Minnesota Lottery hosting Ultimate Fan Jan event before Vikings game – The Mighty 790 KFGO
MINNEAPOLIS (KFGO) – People will have the chance to win $100,000 and meet Jan the Ultimate Vikings Fan at US Bank Stadium Plaza this weekend.
Ultimate Fan Jan became known for her Jan Cave and Jared Allen Diorama commercial.
The Minnesota Lottery is hosting Vikings Tailgate with Ultimate Fan Jan from 9 a.m. to noon Sunday. Fans can walk the purple carpet, meet Jan, and buy scratch-off tickets. People who buy $10, $20, or $40 worth of tickets will get a free gift while supplies last.
Lottery players with non-winning tickets can enter a 2nd chance drawing for a chance to win cash, Vikings season tickets, and team gear.
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XRP Price Sentiment Wavers, SUI Price Prediction Slows, BlockDAG Presale Hits $407M – Crypto Economy
Home – Crypto Presales – XRP Price Sentiment Slows, SUI Price Prediction Stuck, BlockDAG’s Awakening Testnet Pulls $407M Support
XRP has been battling uneven demand despite upgrades in utility, and XRP price sentiment shows traders are split on whether momentum can really stick. Sui is also stuck in a similar loop, where each SUI price prediction points to upside but often clashes with fears of supply pressure. Both coins have strong communities, but they also carry doubts about stability.
So, what if there’s a project that flips the order and proves itself before the main event? That’s exactly what BlockDAG is doing. Instead of waiting for its mainnet, the Awakening Testnet is rolling out real infrastructure, ledger upgrades, explorer tools, miner integration, and account abstraction, all live.
This isn’t just testing; it’s early access to a crypto to explode. The prequel is already attracting the kind of attention most launches dream of, and it’s giving participants first-mover visibility.
Most projects keep their best features hidden until mainnet, but BlockDAG is already putting its architecture to work in the Awakening Testnet. This prequel isn’t a simple trial run; it is live infrastructure with core protocols, explorer tools, and miner integration all operating under real conditions.
By removing the old UTXO model and streamlining how transactions are stored and managed, BlockDAG has built a cleaner, faster ledger that proves scalability before launch. That is why early participants are treating this stage like a front-row ticket to a crypto to explode.
The big draw is visibility. Every transaction, miner connection, and vesting contract can be tracked in real time. That level of transparency is rare before a project launches, and it builds confidence that the systems can handle serious adoption. For early backers, this means more than testing—it is shaping how the network is built, with influence and rewards tied directly to involvement.
Then there is the presale. BlockDAG has already raised over $407 million, selling coins through structured batches that started at just $0.001 and now sit at $0.03 in batch 30. With a listing price set at $0.05, early buyers are already looking at a potential 2,900% return from the first batch, and more upside remains before the sale closes. But the current limited-time entry price is $0.0013. Add to that $40 million raised in the last month, and momentum is undeniable.
The Awakening Testnet proves BlockDAG isn’t asking investors to wait for validation; it is delivering it now. With the presale live and infrastructure already performing, this looks like the crypto to explode while others are still promising what they might one day deliver.
The discussion around XRP continues to focus on confidence, and at the moment, XRP price sentiment remains caught in a tug-of-war. Supporters point to utility upgrades and ongoing adoption news as reasons to hold for the long term.
At the same time, demand has not been steady, and each rally quickly runs into resistance levels that trigger doubt among traders. This inconsistency has left many questioning whether XRP can generate enough momentum to push into a strong new trend or if it will keep slipping back into the same trading ranges.
The bigger challenge is the lack of clarity on where momentum comes from next. XRP price sentiment shows a market split between those expecting upside and those wary of sudden drops if volume dries up.
Without steady catalysts to drive interest, XRP risks staying stuck in range-bound trading even as the broader market strengthens. That uncertainty has investors scanning for other opportunities that can deliver clearer growth signals and stronger returns. With competing projects showing transparent adoption metrics and defined roadmaps, XRP must overcome this hesitation or risk being overshadowed by assets that look more decisive.
Sui is currently trading around $3.65–$3.70, and analysts remain split on where it goes next. Technical charts show resistance near $3.85, with a possible rally toward $4.30 if demand increases.
On the downside, some warn of a drop back to the $3.10–$3.20 range if support fails. This is why every SUI price prediction right now feels like a balance between potential and risk. Traders acknowledge the upside but point to short-term token unlocks and uneven trading volume as factors keeping the coin from building a sustained uptrend.
Looking into Q4 2025, forecasts place Sui in the $5–$6 range if adoption and ecosystem growth continue at the current pace. Longer-term outlooks stretch even higher, with some predicting double-digit prices by 2027–2030.
Still, those projections depend heavily on consistent catalysts that have yet to materialise. Each SUI price prediction today is less about excitement and more about whether on-chain growth and broader market confidence will align. Until that happens, Sui remains a promising project under pressure to deliver proof that it can sustain its momentum.
XRP continues to struggle with uneven demand, and XRP price sentiment reflects that uncertainty as rallies face resistance and traders remain cautious. Sui sits in a similar spot, where every SUI price prediction highlights both potential gains and the risk of short-term pullbacks. Both coins are talked about, but neither has shown the kind of consistent momentum that convinces new buyers to pile in.
That is where BlockDAG separates itself. By turning its Awakening Testnet into a live proving ground, it is already doing what others only plan for after launch. With UTXO removal, explorer tools, and miner integration all active, it is showing real scalability before mainnet. Add in a presale that has raised $407 million and is still open, and it is easy to see why many believe this is the crypto to explode, while others remain stuck in hesitation.
Presale: https://purchase.blockdag.network
Website: https://blockdag.network
Telegram: https://t.me/blockDAGnetworkOfficial
Discord: https://discord.gg/Q7BxghMVyu
This article contains information about a cryptocurrency presale. Crypto Economy is not associated with the project. As with any initiative within the crypto ecosystem, we encourage users to do their own research before participating, carefully considering both the potential and the risks involved. This content is for informational purposes only and does not constitute investment advice.
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US To Recognize Only Civil Marriages For Asylum Seekers, Refugees Seeking Spousal Immigration From July 3 – gistlover.com
The United States Citizenship and Immigration Services (USCIS) has introduced a major change to its policy regarding marriage recognition for asylum seekers and refugees.
New Rule Effective July 3, 2025
Beginning July 3, 2025, USCIS will only acknowledge civil marriages that are legally registered when assessing derivative applications for immigration benefits tied to asylum or refugee status. This change could notably affect applicants from countries where marriages are frequently conducted through traditional or religious customs without civil registration.
What the Policy Entails
In its revised Policy Manual, USCIS now mandates that, to qualify for immigration benefits, a marriage must be legally valid in the place it was performed.
“We are revising guidance in Volume 4 of the USCIS Policy Manual concerning valid marriages involving a principal refugee or asylee and their spouse,” the agency stated. “From now on, only marriages that are legally recognized by the jurisdiction in which they were performed will be accepted for immigration purposes.”
This means that customary or religious marriages not formally recorded under civil law will no longer meet the standard required for spousal immigration through asylum or refugee status.
The new requirement will apply to all applications filed on or after July 3, 2025, including those that are already submitted but still under review.
Who Is Most Affected?
The policy change is expected to significantly impact the following groups:
Rationale Behind the Update
USCIS said the revision brings its policies in line with existing legal interpretations and aims to uphold the integrity of the immigration system by minimizing fraudulent marriage claims.
The agency also pointed to broader administrative goals, noting alignment with directives under the Trump administration, such as Executive Order 14148, which revoked earlier immigration policies, and Executive Order 14163, which outlines a new approach to refugee admissions.
Guidance for Applicants
USCIS encourages individuals planning to file spousal-based asylum or refugee applications to take the following steps:
By complying with these updated requirements, applicants can improve their chances of successful immigration processing under the new rules.
Copyright © 2025 Gistlover Media. All Rights Reserved
Pi Network coin price prediction 2025-2050: Third-party price target – Capital.com
Bitcoin News: Analyst Predicts ‘Uptober’ Rally for BTC Regardless of FOMC Decision – CoinDesk
Will Pi Network’s TOKEN2049 Spotlight Trigger a Price Rally? – BeInCrypto
Written by
Kamina Bashir
Edited by
Harsh Notariya
Dr. Chengdiao Fan, co-founder of Pi Network, has been confirmed as a speaker at the upcoming Token2049 crypto conference.
This development has reignited speculation about a potential short-term price recovery for Pi Coin (PI) amid its ongoing decline.
In an official blog, the Pi Core Team confirmed that, in addition to Dr. Fan’s participation as a speaker, Pi Network will also serve as a Gold Sponsor of the event. TOKEN2049 is one of the largest global conferences in the cryptocurrency and blockchain industry.
The event brings together founders, executives, developers, investors, and regulators to discuss the state of the crypto ecosystem, future innovations, and global trends. This year, TOKEN2049 will occur in Singapore from October 1 to 2.
Dr. Chengdiao Fan, one of two Founders at Pi Network, will be a speaker at the TOKEN2049 conference, which takes place on October 1-2 in Singapore! https://t.co/npzT9pDUiJ
As one of the largest crypto events in the world, this conference is a great opportunity for Pi Network to…
The team highlighted that Dr. Fan’s talk will focus on blockchain’s real-world utility, exploring current Web3 challenges and solutions for driving meaningful innovation. Furthermore, they stressed that this move will strengthen the Pi Network’s presence at the event. It also shows the network’s commitment to connecting with the wider Web3 space and the Pi community.
Dr. Fan’s participation provides a platform to present Pi Network’s outlook on real-world use cases, community growth, and the broader path toward blockchain adoption.
“As the event approaches, further details regarding Dr. Fan’s session will be shared through Pi Network’s official channels. For now, confirmation of both sponsorship and founder participation marks an important step in Pi’s growing engagement with the wider blockchain ecosystem,” the blog read.
The development has raised optimism among the Pi Network community.
“My expectations? An update on the Pi Network roadmap and now that Pi is on the market, insights into what the project aims to achieve in the coming years,” Dr Altcoin wrote.
Notably, many hope this participation might even translate into a short-term price surge.
“PI can be bought on dips! The founder of PI will attend the conference in October, and as usual, there will be a short-term surge!” another Pioneer added.
Another community member noted that Pi’s price could experience volatility in the 15 days leading up to TOKEN2049. This is in line with previously observed patterns.
Pi co-founder Nicolas Kokkalis’s appearance in May on Consensus 2025 also fueled a price rally in the days leading up to the event. However, prices dropped sharply afterward in a typical ‘sell the news’ event.
Meanwhile, BeInCrypto Markets data showed that the value of Pi Coin has increased 0.13% over the past 24 hours. This rise comes amid a broader 19.2% monthly decline.
Nonetheless, the rising exchange supply and upcoming token unlocks could threaten any potential price recovery. Thus, while the event may spark short-term price moves, the lasting impact will depend on the network’s ability to deliver real progress beyond the conference.
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[OUT] Kerala Bumper Lottery Result Today 17.09.2025 LIVE: Dhanalekshmi DL-18 Wednesday Bumper Lucky Draw DECLARED At 3 PM – 1 Crore First Prize, Check Full Winners List – Zee News
KERALA LOTTERY RESULT 17-09-2025 LIVE: The Kerala State Lottery result for the “Dhanalekshmi DL-18 draw on Wednesday, September 17, 2025, is scheduled to be announced at 3 PM. This lottery draw is part of the seven weekly draws held in Kerala. The alphanumeric code assigned to this specific lottery is “DL,” incorporating both the draw number and the code. The first prize for the fortunate winner of this draw is a bumper 1 Crore rupees. Below, you can find the comprehensive list of winners (Ticket Numbers) for the Kerala ‘Dhanalekshmi DL-18’ lottery draw.
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Kerala Lottery Results Today 17-09-2025: The Kerala Dhanalekshmi DL-18 Bumper Lottery result has been declared today by the Kerala State Lottery Department. The lucky draw for the Dhanalekshmi DL-18 lottery was held at 3 PM today, Wednesday, September 17, at Gorky Bhavan, near Bakery Junction, Thiruvananthapuram. The first prize winner will take home a whopping ₹1 Crore. The Dhanalekshmi lottery is one of the seven weekly lotteries conducted by the Government of Kerala and is held every Wednesday. Each ticket costs ₹50, and the draw is represented by the code “DL”, followed by the draw number. You can verify the results at statelottery.kerala.gov.in.
The live results and full list of winning numbers for Dhanalekshmi DL-17 Bumper Draw will be available soon. Check if you’re among the lucky winners below:
Kerala Lottery Result 17-09-2025: FULL LIST OF WINNING NUMBERS FOR DHANALEKSHMI DL-18 BUMPER Draw
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Kerala Lottery Result – LUCKY NUMBER FOR 1ST PRIZE OF ₹1 CRORE IS:DS 195753
Kerala Lottery Result – LUCKY NUMBER FOR 2ND PRIZE OF ₹30 LAKHS IS: DV 256044
Kerala Lottery Result – LUCKY NUMBERS FOR 3RD PRIZE OF ₹5 LAKH ARE:DU 807077
Kerala Lottery Result – LUCKY NUMBERS FOR CONSOLATION PRIZE OF ₹5,000 ARE:
DN 195753
DO 195753
DP 195753
DR 195753
DT 195753
DU 195753
DV 195753
DW 195753
DX 195753
DY 195753
DZ 195753
(For The Tickets Ending with The Following Numbers below)
Kerala Lottery Result – LUCKY NUMBERS FOR 4TH PRIZE OF ₹ 5000 ARE: 0346 0466 1001 1459 2014 2525 2672 3203 3224 3320 3420 3630 4087 4384 4472 4822 4952 7327 7441 8980
Kerala Lottery Result – LUCKY NUMBERS FOR 5TH PRIZE OF ₹2,000 ARE: 1618 2091 3064 4081 4396 9405
Kerala Lottery Result – LUCKY NUMBERS FOR 6TH PRIZE OF ₹1,000 ARE: 0143 0191 0553 0695 0701 1562 2120 2769 2832 3282 4117 4162 4211 4980 5515 6057 6144 6275 6604 6655 6829 7096 7546 7598 7614 8147 8330 9132 9201 9761
Kerala Lottery Result – LUCKY NUMBERS FOR 7TH PRIZE OF ₹500 ARE: 0048 0188 0298 0345 0456 0583 0705 0805 0899 1047 1191 1636 1683 1796 1798 2116 2326 2383 2506 2587 2904 3210 3222 3319 3384 3864 4225 4275 4373 4447 4533 4559 4930 4949 4977 5095 5177 5197 5236 5245 5264 5452 5633 5955 6095 6129 6551 6822 6862 6946 7138 7154 7155 7172 7304 7400 7528 7569 7618 7752 7804 7989 7992 8008 8054 8143 8344 8646 9041 9068 9171 9598 9713 9751 9970 9977
Kerala Lottery Result – LUCKY NUMBERS FOR 8TH PRIZE OF ₹200 ARE: 0023 0177 0238 0247 0614 0743 0780 0934 1008 1054 1254 1303 1433 1563 1650 1686 1695 1696 1926 2085 2320 2420 2487 2560 2568 2622 2658 2728 2752 2828 2914 2931 3005 3065 3134 3161 3243 3308 3327 3504 3523 4001 4010 4079 4144 4218 4686 4888 4899 4912 5055 5553 5559 5709 5742 5876 5920 6226 6241 6415 6514 6554 6658 6733 6904 7128 7318 7330 7479 7547 7550 7756 7783 7909 8066 8220 8431 8526 8527 8722 8729 8732 8744 8855 8923 9032 9038 9191 9232 9235 9464 9606 9649 9675 9812 9966
Kerala Lottery Result – LUCKY NUMBERS FOR 9TH PRIZE OF ₹100 ARE: 0004 0017 0388 0679 0768 0787 0894 0939 0979 1003 1040 1122 1188 1242 1255 1279 1294 1534 1643 1759 1887 1931 1932 2119 2190 2218 2276 2392 2467 2475 2514 2575 2663 2684 2813 2932 3023 3051 3127 3139 3186 3228 3303 3381 3401 3413 3588 3598 3675 3686 3764 3808 3911 4049 4176 4271 4437 4446 4560 4724 4790 5058 5069 5102 5157 5173 5211 5267 5279 5371 5493 5503 5511 5523 5722 5820 5825 5833 5837 5849 5901 5928 5979 6000 6017 6254 6328 6347 6446 6533 6582 6662 6810 6892 6902 6929 7034 7109 7118 7131 7134 7224 7225 7268 7344 7379 7442 7529 7611 7638 7685 7806 7842 8090 8097 8115 8168 8417 8467 8519 8530 8535 8628 8703 8841 8878 9004 9136 9155 9403 9526 9634 9701 9759 9833 9835 9974 9988
KERALA LOTTERY RESULT September 17 TODAY: DHANALEKSHMI DL-18 BUMPER LOTTERY PRIZE DETAILS
Kerala Lottery Result 1st Prize: ₹1,00,00,000 (1 Crore)
Kerala Lottery Result 2nd Prize: ₹50,00,000 (50 Lakhs)
Kerala Lottery Result 3rd Prize: ₹20,00,000 (20 Lakh)
Kerala Lottery Result 4th Prize: ₹1,00000 (1 Lakh)
Kerala Lottery Result 5th Prize: ₹5,000
Kerala Lottery Result 6th Prize: ₹1,000
Kerala Lottery Result 7th Prize: ₹500
Kerala Lottery Result 8th Prize: ₹100
Kerala Lottery Result 9th Prize: ₹50
Kerala Lottery Result – Consolation Prize: ₹5,000
(NOTE: Lottery can be addictive and should be played responsibly. The data provided on this page is for informational purposes only and should not be construed as advice or encouragement. Zee News does not promote lottery in any way.)
Stay Tuned To Zee News For Live And Latest Updates On Kerala Lottery Result
9th Prize Rs.100/-
(Last four digits to be drawn 138 times)
0004 0017 0388 0679 0768 0787 0894 0939 0979 1003 1040 1122 1188 1242 1255 1279 1294 1534 1643 1759 1887 1931 1932 2119 2190 2218 2276 2392 2467 2475 2514 2575 2663 2684 2813 2932 3023 3051 3127 3139 3186 3228 3303 3381 3401 3413 3588 3598 3675 3686 3764 3808 3911 4049 4176 4271 4437 4446 4560 4724 4790 5058 5069 5102 5157 5173 5211 5267 5279 5371 5493 5503 5511 5523 5722 5820 5825 5833 5837 5849 5901 5928 5979 6000 6017 6254 6328 6347 6446 6533 6582 6662 6810 6892 6902 6929 7034 7109 7118 7131 7134 7224 7225 7268 7344 7379 7442 7529 7611 7638 7685 7806 7842 8090 8097 8115 8168 8417 8467 8519 8530 8535 8628 8703 8841 8878 9004 9136 9155 9403 9526 9634 9701 9759 9833 9835 9974 9988
8th Prize Rs.200/-
(Last four digits to be drawn 96 times)
0023 0177 0238 0247 0614 0743 0780 0934 1008 1054 1254 1303 1433 1563 1650 1686 1695 1696 1926 2085 2320 2420 2487 2560 2568 2622 2658 2728 2752 2828 2914 2931 3005 3065 3134 3161 3243 3308 3327 3504 3523 4001 4010 4079 4144 4218 4686 4888 4899 4912 5055 5553 5559 5709 5742 5876 5920 6226 6241 6415 6514 6554 6658 6733 6904 7128 7318 7330 7479 7547 7550 7756 7783 7909 8066 8220 8431 8526 8527 8722 8729 8732 8744 8855 8923 9032 9038 9191 9232 9235 9464 9606 9649 9675 9812 9966
7th Prize Rs.500/-
(Last four digits to be drawn 76 times)
0048 0188 0298 0345 0456 0583 0705 0805 0899 1047 1191 1636 1683 1796 1798 2116 2326 2383 2506 2587 2904 3210 3222 3319 3384 3864 4225 4275 4373 4447 4533 4559 4930 4949 4977 5095 5177 5197 5236 5245 5264 5452 5633 5955 6095 6129 6551 6822 6862 6946 7138 7154 7155 7172 7304 7400 7528 7569 7618 7752 7804 7989 7992 8008 8054 8143 8344 8646 9041 9068 9171 9598 9713 9751 9970 9977
6th Prize Rs.1,000/-
(Last four digits to be drawn 30 times)
0143 0191 0553 0695 0701 1562 2120 2769 2832 3282 4117 4162 4211 4980 5515 6057 6144 6275 6604 6655 6829 7096 7546 7598 7614 8147 8330 9132 9201 9761
5th Prize Rs.2,000/-
(Last four digits to be drawn 6 times)
1618 2091 3064 4081 4396 9405
4th Prize Rs.5,000/-
(Last four digits to be drawn 20 times)
0346 0466 1001 1459 2014 2525 2672 3203 3224 3320 3420 3630 4087 4384 4472 4822 4952 7327 7441 8980
3rd Prize Rs.5,00,000/- [5 Lakhs]
(Common to all series)
DU 807077 (PATTAMBI)
2nd Prize Rs.30,00,000/- [30 Lakhs]
(Common to all series)
DV 256044 (ERNAKULAM)
1st Prize Rs.1,00,00,000/- [1 Crore]
Kerala lottery tickets
(Common to all series)
DS 195753 (MALAPPURAM)
Prize winners should check their winning numbers against the results published in the Kerala Government Gazette. To claim their prizes, they must submit the winning tickets within 30 days.
A ticket with multiple security features can prevent claims if damaged. So keep the ticket safe. Those who won the prize less than Rs.5000 should approach any lottery shop in Kerala with the ticket to collect the amount. If the prize is more than 5000 then the ticket and identity documents should be brought to any bank or government lottery office.
If the prize money is less than Rs 5,000, the winners can claim the money from any lottery shop in Kerala. If the amount won is above Rs 5,000, the winners will have to surrender their tickets before a bank or government lottery office with id proofs. The prize winners are advised to verify the winning numbers with the results published in the Kerala Government Gazatte and surrender the winning tickets within 30 days.
The Akshaya Lottery is held on Sunday, the Win-Win Lottery is held on Monday, the Sthree Sakthi Lottery is held on Tuesday, the Fifty-Fifty Lottery is held on Wednesday, the Karunya Plus Lottery is held on Thursday, the Nirmal Lottery is held on Friday, and the Karunya Lottery is held on Saturday. Unfortunately, the government temporarily halted the sale of the Pournami lottery and introduced a new programme in the Monthly Lottery called Bhagyamithra Lottery. Live updates for the Kerala lottery results will start to appear from 3.05 pm on ZEE NEWS ENGLISH site.
Stay tuned for live updates on the Kerala Lottery Result for September 17, 2025. It’s crucial to note that online purchasing of Kerala lottery tickets is prohibited, carrying potential legal consequences. Engaging in such practices may lead to penalties imposed by legal authorities, as the state government strictly prohibits online selling and purchasing of lottery tickets.
The Kerala Lottery Result for Dhanalekshmi DL-18 is set to be drawn today. The public can view the Winning Number post at 2.55 pm during the live broadcast of Kerala Lottery Today. The announcement for the Kerala Lotteries Result today, dated September 17, 2025, is expected to follow shortly.
Stay informed on all the latest news, real-time breaking news updates, and follow all the important headlines in india news andworld News on Zee News.
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Diagnosing GIST: Key Challenges and Treatment Insights – Curetoday
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Dr. Breelyn Wilky explains how vague symptoms and testing challenges delay GIST diagnoses; however, molecular testing can help guides treatment decisions.
Dr. Breelyn Wilky, an associate professor of medicine in the Department of Medical Oncology at the University of Colorado, Anschutz Medical Campus, explains the challenges patients with rare cancers like gastrointestinal stromal tumors (GIST) often face.
One of the biggest hurdles is simply getting the right diagnosis. Symptoms like belly pain, heartburn, or feeling tired are very common and usually caused by something else. Because of that, doctors and patients don’t always think about rare cancers like GIST right away. That’s why awareness is so important, according to Wilky.
A biopsy is crucial to confirm the diagnosis, but sometimes, the tissue sample isn’t clear-cut, and doctors may need to get a second opinion to be sure.
Molecular testing to identify the specific mutation driving the tumor is also key to choosing the right treatment. If the first biopsy doesn’t provide enough material, patients might need another one.
Dr. Wilky, who also serves as the director of Sarcoma Medical Oncology, deputy associate director for Clinical Research, and the Cheryl Bennett and McNeilly Family Endowed Chair in Sarcoma Research at the University of Colorado Cancer Center, UCHealth, stresses that a more streamlined process is vital for patients.
There are many challenges when you're diagnosed with a rare cancer. First of all is the awareness piece, like making sure you actually get diagnosed with the right rare cancer is super, super important. When you're first presenting with symptoms, they can be very vague, like abdominal pain, heartburn, or feeling more tired than usual. These are very common symptoms, and in about 99.9% of cases, they’re caused by something other than a rare cancer. Even getting to the point of thinking this patient might have cancer based on symptoms, if they have any symptoms at all, is a big leap.
Then, to go from concerns about more common cancers, like pancreas, stomach, or colon cancer, to considering a GIST tumor growing from the small bowel and causing a weird bloating sensation, that’s even less likely. Part of the challenge is simply knowing that GIST exists, that it’s a real, rare entity with recognizable patterns and that it can be diagnosed.
Sometimes things get confusing. We say, “Tissue is always the issue,” meaning that if you have a scan or symptoms concerning for GIST, doctors will usually do a scope to get tissue and a biopsy. It’s crucial to have that biopsy reviewed to confirm whether there’s a GIST. In some cases, it’s very difficult to tell, and the sample needs to be sent out for a second pathology opinion.
Getting molecular testing and knowing the mutation that’s driving your GIST is extremely important for treatment. If you’re going to start therapy, we recommend testing the tumor, if at all possible. Sometimes the initial biopsy is very small and may not provide enough material. That’s when you should talk with your doctor about whether a second biopsy is needed.
For more news on cancer updates, research and education, don’t forget to subscribe to CURE®’s newsletters here.
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