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Gastrointestinal Stromal Tumor: Comprehensive Patient Guide – CUREtoday.com

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This patient guide explains gastrointestinal stromal tumors, covering diagnosis, treatment options, targeted therapies and practical care tips.
Gastrointestinal stromal tumors, or GISTs, are rare cancers that form in the digestive tract, most commonly in the stomach or small intestine. They originate from interstitial cells of Cajal, which help coordinate muscle contractions in the gastrointestinal tract. GISTs vary widely in size, location, and aggressiveness. Early detection can improve outcomes, but many patients are diagnosed after experiencing symptoms such as abdominal pain, bloating, nausea, fatigue, gastrointestinal bleeding, or anemia. Some tumors are discovered incidentally during imaging for other conditions.
GISTs are staged based on tumor size, location, mitotic rate (how quickly tumor cells divide), and spread to lymph nodes or distant organs. Genetic testing is also important. Mutations in the KIT or PDGFRA genes are common and directly influence treatment choices. Accurate diagnosis and staging are essential for developing an effective treatment plan.
Diagnosis usually begins with imaging tests such as CT scans or MRIs to locate the tumor and assess its size and spread. Endoscopy may be performed for tumors in the stomach or small intestine, allowing direct visualization and tissue sampling. A biopsy confirms the diagnosis, and molecular testing identifies mutations that predict responsiveness to targeted therapies.
Laboratory tests may also be performed to evaluate overall health and organ function. Early discussion with your oncologist about genetic testing is important because it can guide treatment selection and clinical trial eligibility.
“They are not common tumors; they are tumors of the supporting structure of the gastrointestinal tract, kind of like the scaffolding. And again, they are, by and large, benign entities, but they certainly have significant malignant potential. So when we see them, and we see them often enough in patients because they are often found as lumps and bumps during an endoscopy, further characterization is definitely warranted,” Dr. Rosario Ligresti, the chief of Gastroenterology and Interventional Endoscopy at Hackensack Meridian Health, explained in an interview with CURE.
Targeted therapies can cause side effects, which vary in severity.
Patients are encouraged to report side effects promptly. Dose adjustments, supportive medications, or lifestyle strategies can help manage symptoms. Open communication with your care team can improve quality of life and allow continued therapy.
“Even if you had curative surgery, number one, you need surveillance. Number two, some patients need treatment to decrease risk of recurrence. And number three, it’s best to also have genetic follow-up, to make sure there is no inherited risk for yourself and also for other family members,” Dr. Weijing Sun, associate director at the University of Kansas Cancer Center, said in an interview with CURE.
GIST treatment is highly personalized. Surgery is the mainstay for localized tumors, while targeted therapies like Gleevec, Sunitinib, and Regorafenib play a critical role in high-risk or metastatic disease. Genetic testing informs treatment selection, and careful monitoring can help manage side effects. Patients are encouraged to maintain open dialogue with their oncologist, ask questions about new therapies, and explore supportive care resources to maintain quality of life throughout treatment.
Editor’s Note: This guide is designed to be a starting point. Your personal experience will be unique. By using this information as a foundation for your discussions, you can partner with your oncologist to make the best decisions for your health.
For more news on cancer updates, research and education, don’t forget to subscribe to CURE®’s newsletters here.
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Sharing hearts, food, cooking tips and culture – Onkaparinga Now

Published on 17 October 2025
Every month, the Christie Downs Community House kitchen fills with the sound of sizzling pans, the aroma of spices, and the chatter of women speaking in both English and their native tongues.
It’s here that the Ahmadiyya Muslim Women’s Association hosts its free, monthly Meet & Greet a Muslim cooking classes – a chance for women to connect, share stories and discover the harmony of South Asian culture through food, conversation and friendship.
For volunteer host Mehreen Rehman, Secretary of Interfaith Harmony and External Affairs, the most recent class carried special meaning. “The word Islam translates to peace,” she says, reflecting on its alignment with the International Day of Peace on 21 September.
“We build bridges through the universal language of food – one meal and one conversation at a time. We open our hearts to the wider community and our door to the local women that come together.”
Participants watch the Muslim women prepare dishes such as Chicken Pulao (fragrant rice dish), Channa Chaat (chickpea salad), Raita (yogurt-based side dish) and the sweet treat of syrup-soaked Gulab Jamun balls. Recipes are eagerly noted down, cooking tips are exchanged across cultures, and when the cooking is done, everyone sits shoulder-to-shoulder at a long table to share the delicious feast they’ve created together.
“Peace isn’t the absence of war, it’s the presence of love,” explains one young volunteer Mehroz Chaudhary. “You foster true love through conversations and sharing personal experiences. Food opens people’s hearts and we always find how much we share in common.”
Running for the past 5 years, the 2-hour monthly events provide a safe, women-only space where conversations flow well beyond food. Women share stories about motherhood, health, work-life balance, faith and wellbeing, resulting in a sense of connection that continues long after the plates are cleared away.
Volunteer Mehroz says, “I think this community that we’ve built is the perfect setting for dialogue between people from vastly different cultures. We are always meeting new people and seeing new faces.”
Each class also includes a short presentation about Islamic culture. Mehreen shares the phrase “Love for all, hatred for none”, alongside books includingThe Holy Qur’an – which has been translated into more than 70 languages by the Ahmadiyya Muslim Community.
She explains in simple, everyday words how the traditional text inspires her:
“Your brightness comes from your morals and moral integrity, regardless of colour, race or age. It encourages mutual understanding instead of conflict. Peace, coexistence and respect bring everyone around the table to share experiences.”
Born in England, raised in Pakistan from the age of 4, and later living in Yemen before moving to Australia with her husband in her early twenties, Mehreen knows firsthand the power of food to connect people across cultures. “Sharing food is an important part of our culture and every celebration,” she says.
To attend a free cooking class, contact amw.adlsouth@gmail.com
This is not the only warm meal offered through Christie Downs Community House. Humanity First Australia hosts free dinners every second and fourth Wednesday of the month, led by Saleem Shaukat, State Director of Humanity First. Everyone is welcome.

COMMUNITY – Connected, supportive communities
To celebrate the one-year anniversary of the Community Vision 2034, council is interviewing locals who are making Onkaparinga the kind of place they’d like to live now and over the next decade. The Ahmadiyya Muslim Women’s Association cooking class brings to life the Community Vision goal of “enhancing connections across diverse cultures and identities.”

Top to bottom:
– Mehreen Rehman, Secretary of Interfaith Harmony and External Affairs, Ahmadiyya Muslim Women’s Association.
– Monthly Meet & Greet a Muslim cooking classes.
– Everyone sits down to a feast of Chicken Pulao (fragrant rice dish), Channa Chaat (chickpea salad), and Raita (yogurt-based side dish) followed by dessert.
– The sweet treat of syrup-soaked Gulab Jamun balls for dessert.
– The kitchen is full of fresh ingredients and the aromas of spices.
Sign up for our monthly email newsletter to get stories about local issues, events and people, direct to your inbox.

Local animal lovers are accessing life-changing support for their pets in times of need – see how you can too at a Community Connections Day on Wednesday 22 October.
Southern superstars have been winning big from McLaren Vale to Mongolia, for sausage rolls to scarecrows and everything in between.
In backyards across Onkaparinga, volunteers are rescuing unwanted or excess fruit to save food from going to waste and help feed the community.
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XRP Price Movements: Trends and Predictions – OneSafe

XRP has been on quite the rollercoaster ride lately, hasn’t it? Just a few days ago, we saw it tumble down to the $1.50 range, only to bounce back up to about $2.38. But let’s be real, it’s still struggling to break past that all-important $3.00 threshold. This makes me think there might be more at play here.
According to market strategist TraderJB, all of this is part of a larger corrective structure. Apparently, XRP has been in a 10-month corrective phase broken down into three waves labeled (W), (X), and (Y). The recent price drop could have cleared out a lot of leveraged long positions, possibly setting the stage for recovery.
When it comes to predicting XRP’s future movements, TraderJB offers two scenarios. The first is that the correction has already ended, and we could see another upward trend soon. The second scenario is a bit more pessimistic. It suggests we may have to wait for two more corrective waves before any significant recovery occurs, pushing the timeline out to mid-2026.
Currently, XRP sits around $2.38. If it can decisively move above $2.80 to $3.00, we might see some bullish momentum. But if it drops below that recent $1.50 low, it could be a sign that the correction is still in play. History does seem to back this up, as past cycles have shown similar behavior.
Of course, XRP doesn’t exist in a vacuum. Regulatory changes, market sentiment, and broader economic factors all play a role. For instance, any legal developments related to Ripple can have a dramatic impact on XRP prices. And with the upcoming MiCA regulation, there are compliance concerns that could affect stability.
Market sentiment is another wild card. Sudden price swings due to fear or greed aren’t always captured by technical analysis. Plus, macroeconomic trends and political events can also influence investor behavior.
What can organizations do to manage the volatility that comes with cryptocurrencies? Well, here are a few strategies:
Diversifying Treasury Assets: DAOs should spread their treasury across various assets, including stablecoins and established cryptocurrencies, to lessen the impact of any single asset’s volatility.
Financial Modeling and Budgeting: Developing solid financial models helps organizations forecast expenses and predict cash flow needs so they can meet obligations, even during market downturns.
Risk Assessment: Implementing formal risk management frameworks allows organizations to identify and mitigate various risks. Regular assessments and contingency planning are key.
Governance and Community Engagement: Strong governance structures and community involvement can enhance an organization’s adaptability to market fluctuations.
Regulatory Compliance: Navigating regulations is crucial. Consulting legal experts and maintaining transparency helps avoid legal and reputational risks.
The integration of cryptocurrencies into various sectors is picking up speed, particularly in payroll and payment systems. Paying salaries in cryptocurrencies is becoming a trend among tech workers and startups. Some companies are even exploring hybrid systems that mix fiat, stablecoins, and volatile cryptocurrencies to balance risks with blockchain efficiency.
With the upcoming MiCA framework providing more clarity, we might see wider adoption across payroll systems. But organizations must remain cautious, investing in compliance and robust risk management to navigate the evolving landscape successfully.

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Mamdani debates Cuomo in NYC mayoral race – BBC

New York City mayoral candidates Zohran Mamdani, Andrew Cuomo and Curtis Sliwa have wrapped up a fiery debate at Rockefeller Center
Mamdani and Cuomo both say they can fight President Trump to protect New Yorkers, but give him credit for Gaza ceasefire
Cuomo says Mamdani's support for Palestinians means "from the river to the sea," as Mamdani says he will represent all New Yorkers, including Jews
Mamdani and Cuomo agree that the National Guard is not needed in NYC, as Sliwa says sending the National Guard to subways was the right thing to do
Asked to pitch businesses to stay in New York City, Mamdani stresses quality of life, and Cuomo says city must avoid socialism and be a partner
A lightning-question round hits on weed purchases, bodega breakfast orders and favoured sports teams
On the problem of affordability in New York, candidates went through topics from rental policy to public transportation.
Edited by Brandon Livesay and Caitlin Wilson with Kayla Epstein and Grace Goodwin at the debate
Aisha Sembhi, BBC Verify
One of Zohran Mamdani’s key pledges is for free bus travel for all New Yorkers, if he becomes mayor.
During the debate, Andrew Cuomo said about his rival’s plan, "It's been done before in other cities. It's been a disaster, they stopped".
Free bus travel has been implemented in several US cities. After a 2020 trial period in Albuquerque, New Mexico, the city made the scheme permanent in 2023 – and reported a 20% increase, external in ridership in 2024.
Richmond, Virginia has also been operating a ‘Zero Fare’ model since 2020 – though the city has recently begun promoting community fundraisers to keep the system free.
The free bus model was trialled in Kansas City but the city council has announced that fares would be reintroduced in 2026.
Mamdani took part in a fare-free pilot scheme on five bus routes in New York.
A report into the pilot, external by the Metropolitan Transportation Authority (MTA) found that the number of people using the service increased on all routes, however the average speed of the buses decreased.
Cuomo also claimed free bus models result in buses becoming "mobile homeless gathering places". There was no mention of homeless passengers in the MTA report.
Nada Tawfik
Reporting from New York

After Andrew Cuomo lost to Mamdani in the Democratic primary, he announced in a video that he would run in the general election as an independent, promising a new and improved campaign after an uninspired primary run.
In comparison to Mamdani, who seemed to be on a mission to cover every inch of the city, Cuomo had little interaction with voters.
So, in the video he declared that he would be going out on the streets every day to hear from New Yorkers because it was his responsibility to earn their votes.
But it’s not been easy for the well-known former governor to change his public image. And the harder he’s tried, with varying approaches, the more it’s highlighted the glaring generational divide between the two campaigns.
After one ad where he helped a man jump-start his car, the right-leaning tabloid, the New York Post, noted the video "crashed and burned", and was blasted as "cringe and inauthentic".
Later, he was criticised for using AI, rather than NY artists, to create an ad portraying him doing various jobs around the city before the real Cuomo on camera says, "There are a lot of jobs I can’t do. But I’m ready to be your mayor on day one."
He’s hoping by highlighting Mamdani’s inexperience relative to his years in government, public safety and job creation, along with affordability, he’ll sway voters.
By Joshua Cheetham
Earlier in the debate, the candidates were asked about whether they would accept any deployment of the National Guard to the streets of New York.
Zohran Mamdani said he wouldn’t and added: "If it was safety that Donald Trump was concerned about, he would send them to the eight out of 10 states that have the highest levels of crime in this country. But he won’t because they’re all run by Republicans."
We’ve taken "run by Republicans" to mean a state with a Republican governor and a Republican-majority legislature.
According to the latest figures from the Justice Center , externalthink tank, in 2024 Alaska – a Republican-run state – had the highest levels of violent crime in the country, with 724 violent incidents per 100,000 people.
Behind it came New Mexico, Tennessee, Arkansas, Louisiana, California, Colorado, Missouri, Kansas and South Carolina.
Five of these are Republican run, three are run by Democrats, and one, Kansas, is split between the two parties.
So a majority are Republican run but we don’t make it eight out of 10.
Grace Eliza Goodwin
Reporting from New York

In a gaggle with reporters after the debate, Sliwa says he thinks he did "extraordinarily well" tonight.
"I obviously had to get my words in edgewise because you had two kids in the schoolyard who just wanted to continue their battles from the primary."
Sliwa dug into Cuomo for losing the primary and continuing to run as an independent, saying "he doesn't understand the meaning of ‘no’ in so many ways."
Sliwa again mispronounces Zohran Mamdani’s first name, after Mamdani corrected him several times during the debate.
Early voting in the NYC mayor’s race is set to begin next week, so let’s have a look at how each of the three major candidates are doing in the polls.
The most recent polling, conducted by Quinnipiac University, external between 3-7 October, suggests Zohran Mamdani has widened his lead to double digits over Andrew Cuomo with Curtis Sliwa trailing behind.
Here’s where they stand with likely voters according to the poll:
Mamdani – 46%Cuomo – 33%Sliwa – 15%
With that, the first New York City mayoral debate has finished. Stick with us for more top lines from this campaign and reactions and analysis from tonight's head-to-head.
For more stories from the US and around the world, follow BBC News US on WhatsApp.
Bodegas (corner stores with deli counters) are an institution in New York City.
The candidates are asked what their go-to breakfast sandwich order is:
Cuomo and Sliwa both said they order an egg and cheese on a roll – with no salt.
Mamdani spiced things up, saying he gets an egg and cheese on a roll with jalapeños.
In New York City, the use of recreational marijuana is legal. The moderators ask the candidates if they've ever bought a product from one of these dispensaries.
Mamdani smiles and says yes, he has legally purchased recreational marijuana.
Cuomo says he has not.
Sliwa says "when he was shot five times" he did use medical marijuana.
The candidates are now being asked about calls to 911 – which routes responses to emergency first responders, including police – for people who appear to be dealing with mental health struggles.
Mamdani said he wants to take non-violent mental health calls out of the police department and instead send mental health experts to the scene.
Moderators push him on this, asking who will make the call on what situations are violent. He says he will trust 911 operators will make those determinations, along with the mental health professionals.
Sliwa differs, calling Mamdani's plan a "fantasy".
He said mentally ill people need to be "removed" and need mental healthcare and proper homeless shelters.
Cuomo says calls about mentally ill people can turn violent, and there should be social workers and police officers both on the scene.
Sliwa pushes back against Cuomo too, saying it's "not realistic" to deploy both police and mental health professionals.
A bit of confusion here on the debate stage. The moderators ask Cuomo to look into the camera and answer a question within 30 seconds. And then next to him, not looking into the live camera, Sliwa starts to answer.
They tell him it's for Cuomo, who looks confused. He asks which camera to look at, and how long to speak.
He gets a few lines out but his time runs out.
The candidates are now focusing on a hyper-local topic: education policies in the city.
Sliwa says his two 4-year-old sons failed to get into New York's gifted and talented programme – which provides accelerated curriculum for advanced elementary school students – but that didn't hold them back in their education. He adds that there needs to be more slots in the program for New York's kids.
Cuomo says he would expand gifted and talented programs, as well as double the number of specialised high schools.
Mamdani says that his past statements about phasing out the gifted and talented programme were specifically and only about the kindergarten level of the programme, not higher grades.
The candidates are asked who they view as the best modern day US president.
Here are their picks:
Cuomo: Bill Clinton (Cuomo notes he was Clinton's Housing and Urban Development secretary).
Mamdani: Franklin Roosevelt
Sliwa: Ronald Reagan (Sliwa intially misinterprets the question and answers George Pataki, a former governor of New York)
Next, Cuomo addresses accusations of antisemitism around Mamdani. The former governor says many Jewish New Yorkers think Mamdani is antisemitic, but will not answer when asked if he himself thinks Mamdani is antisemitic.
Mamdani responds by saying he has denounced Hamas many times. He accuses Cuomo of making false statements about him, and of sending out anti-Mamdani mailers that artificially lengthened his beard.
Cuomo is now asked what lessons he learned from losing the Democratic primary to Mamdani.
His answer: use social media more in his campaign.
"I did not do enough on social media," he say, saying Mamdani did a better job on TikTok. "But my agenda is exactly the same" as it was during the primary.
Kayla Epstein
US reporter

The candidates are asked how much they use a public service known as 311.
311 is a non-emergency number and website that New Yorkers can use to report issues like potholes, illegally dumped trash, excessive rats, traffic problems, noise, icy streets, and more. The service also allows callers to request assistance for homeless people.
All the candidates say they've called 311, but have mixed reviews of its responsiveness.
In my own experience, the 311 response rate has sometimes been spotty – but this summer they did respond to my request to fix an out-of-order traffic light within an hour.
The candidates are asked what they would do to combat noise complaints in the city that never sleeps.
Cuomo says the ethos in the city right now is "toxic" and "divisive." And to reset that ethos, he says, New York needs greater public safety.
Sliwa says his goal is improve quality of life, by tackling things like trash pile-ups and illegal parking, so that New Yorkers stay in the city and don't flee.
Mamdani says one of the biggest noise complaints in the city is over traffic congestion. If congestion pricing were implemented, he says, it would drop noise complaints in the congestion zone.
The candidates are now talking about taxes.
Cuomo and Sliwa seem to be aligned on attacking Mamdani's tax increase plans.
"You would see New Yorkers on I-95 fleeing to Florida" if Mamdani's tax plan is implemented Cuomo says
Sliwa agrees, saying New Yorkers are being "lured south".
"You gotta cut taxes for people to stay here," he says.
by Joshua Cheetham, BBC Verify
Zohran Mamdani has been heavily criticised, including by President Donald Trump, for his previous comments about the police. This topic was brought up earlier in tonight's debate.
In 2020, during nationwide protests over the killing of George Floyd by a Minneapolis police officer, Mamdani called for the defunding of the New York Police Department.
"We don't need an investigation to know that the NYPD is racist, anti-queer & a major threat to public safety. What we need is to #DefundTheNYPD" he wrote on X that year.
"There is no negotiating with an institution this wicked & corrupt," he wrote, referencing city budget negotiations around proposed cuts to the NYPD.
"Defund it. Dismantle it. End the cycle of violence."
Mamdani has since distanced himself from these comments, saying they were "out of step" with his current platform.
He issued an apology to the NYPD in a Fox News interview yesterday when challenged to do so.
During his campaign, Mamdani has said he does not want to defund New York’s police or reduce headcount, although he plans to cut down on overtime spending.
He has proposed creating a "Department of Community Safety" to shift some responsibilities away from police, and address the root causes of some crimes. The department would focus primarily on mental health services, gun violence reduction, victim services and educational schemes to reduce hate crime.
Mamdani explained during tonight's debate that his views on the topic have evolved since becoming a New York state assemblyman, as he's come to understand the NYPD's work.
Curtis Sliwa has repeatedly mispronounced Zohran Mamdani's first name as the debate has gone on.
Mamdani has corrected him each time. At first, Mamdani politely offered Sliwa the correct pronunciation and said thank you after Sliwa made an effort to say it properly. When Sliwa mispronounced it again, Mamdani has appeared a bit more agitated.
During the primary debates, Mamdani also corrected Cuomo's mispronunciation of his name.
Kayla Epstein
US reporter

We're how halfway through the debate, and the conversation has moved to one of the animating issues of this campaign: affordability.
The candidates are debating everything from rental policy to public transportation. Moderators even asked them to say how much they spent on rent and groceries themselves, as many New Yorkers struggle to afford either.
Cuomo has criticised Mamdani for living in a rent-stablised apartment, even though his parents are wealthy (his mother is the filmmaker Mira Nair).
"If you think that the problem in this city is that my rent is too low, vote for him," Mamdani said of Cuomo. "If you know the problem in this city is that your rent is too high, vote for me."
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Bam Knight player props odds, tips and betting trends for Week 7 | Cardinals vs. Packers – USA Today

Check out these betting trends before placing player prop wagers on Bam Knight for Sunday’s game, which starts at 4:25 p.m. ET on FOX. Knight and the Arizona Cardinals (2-4) take on the Green Bay Packers (3-1-1) in a Week 7 matchup at State Farm Stadium.
National Football League odds courtesy of BetMGM. Odds updated Thursday at 9:59 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.
Gambling involves risk. Please only gamble with funds that you can comfortably afford to lose.  While we do our utmost to offer good advice and information we cannot be held responsible for any loss that may be incurred as a result of gambling.  We do our best to make sure all the information that we provide on this site is correct. However, from time to time mistakes will be made and we will not be held liable. Please check any stats or information if you are unsure how accurate they are. No guarantees are made with regards to results or financial gain. All forms of betting carry financial risk and it is up to the individual to make bets with or without the assistance of information provided on this site and we cannot be held responsible for any loss that may be incurred as a result of following the betting tips provided on this site.  Past performances do not guarantee success in the future and betting odds fluctuate from one minute to the next. The material contained on this site is intended to inform, entertain and educate the reader and in no way represents an inducement to gamble legally or illegally or any sort of professional advice.
Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside. It is your sole responsibility to act in accordance with your local laws.

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XRP Price Today: XRP Consolidates at $2.44 With Key Supply Zones Shaping the Next Move – Brave New Coin

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XRP’s price action is entering a defining moment, sitting at a tight crossroads between major support and resistance levels that could set the tone for its next explosive move.
After a week marked by whale distribution, cascading liquidations, and growing ETF anticipation, XRP price today is holding near $2.44, with traders watching closely for a breakout or a breakdown in the coming sessions.
Recent on-chain data from Glassnode reveals that $2.10 has emerged as a key support level for Ripple XRP, where around 2.54% of the total supply was acquired. On the upper side, $2.80 stands as a strong resistance zone, with nearly 3.97% of supply bought around this price. These levels are acting as natural psychological barriers, reflecting the behavior of long-term holders.
XRP Finds Balance Between $2.10 Support and $2.80 Resistance
Glassnode’s data highlights strong XRP support at $2.10 with 1.65B coins accumulated and key resistance forming at $2.80. Source: Ali Martinez via X
As of October 16, 2025, XRP’s current price remains locked between these levels, supported by a massive $5.8 billion in daily trading volume. Unless a major regulatory or macro catalyst breaks this range, analysts expect the price to continue consolidating within these zones.
Heavy institutional activity has defined XRP’s recent moves. Between October 14 and 15, the price of XRP plunged 6% from $2.49 to $2.41 as large holders distributed over 2.23 billion tokens to exchanges, wiping out nearly $10 billion in market value. This wave of selling triggered forced deleveraging across derivatives markets, cutting open interest in half to $4.22 billion.
Support failed at $2.48–$2.50, triggering cascade liquidations that drove price to $2.40. This institutional exodus, rather than retail panic, has largely shaped recent price action, with funding rates on major platforms turning negative.
From a technical standpoint, Ripple XRP price is hovering near short-term support at $2.40–$2.42, with immediate resistance sitting around $2.55–$2.56. Broader overhead supply remains heavy at $2.65. Volume-weighted metrics suggest buyers have yet to step in decisively, keeping momentum oscillators in oversold territory.
Technical Indicators Suggest Tight Trading Range
A candlestick chart shows XRP/USDT futures signaling a potential pullback to $2 support after peaking near $3.30, driven by sustained bearish divergence. Source: Ali Martinez via X
A clean break above $2.55 could indicate a re-accumulation phase, while holding $2.40 support may lead to sideways trading in the short term. If that support breaks, eyes turn back to the $2.10 zone highlighted by Glassnode as a major accumulation level.
Data from Coinglass highlights a liquidity sweep that cleared lower support zones near $2 earlier this month. This move potentially sets the stage for a rebound, with liquidity clusters around $3.40 acting as the next major upside target if bullish momentum builds.
Traders Eye Post-Liquidity Sweep Rally
XRP has cleared its base, with the next major liquidity wall positioned near $3.40. Source: @Steph_iscrypto via X
A popular crypto analyst, Ali Martinez, pointed out on social media that “a pullback toward $2 could create a prime dip-buying opportunity before the next push higher.” His 12-hour chart on TradingView aligns with expectations of a short-term correction before resuming an upward trajectory seen during mid-2025 rallies.
Market structure remains cautiously bullish. Analysis from trader TurboBull21 identifies $2.32 as a pivotal support that previously preceded a breakout to all-time highs. A decisive bounce from this region could set the stage for a 31% climb toward $3.04 resistance. This aligns with optimistic forecasts tied to Ripple’s upcoming Swell 2025 conference, which involves industry giants like Nasdaq and BlackRock.
XRP Price Forecast Points Toward Potential Breakout
XRP has retested and held $2.32, aiming for a potential 31% rise toward $3.04, which must be reclaimed to confirm a higher high. Source: TurboBullCapital via X
With discussions around XRP ETF approval intensifying and altcoin momentum building, some analysts foresee XRP price prediction 2025 targets surpassing $3 by year-end—contingent on favorable regulatory signals and broader crypto market trends.
For now, XRP today remains range-bound. Traders are closely watching whether $2.40 support can absorb further institutional selling or if new inflows will drive a push above $2.55. The $2.10–$2.80 zone will likely continue to guide short-term sentiment.
Market Outlook: Range-Bound or Breakout Ahead?
XRP was trading at around $2.438, down 2.34% in the last 24 hours at press time. Source: XRP price via Brave New Coin
Should accumulation resume and ETF optimism grow, a breakout beyond $3 remains within reach. However, if selling pressure persists, XRP price forecast scenarios suggest a retest of lower supports before the next bullish leg.
The coming weeks could be decisive in shaping the trajectory of the XRP crypto price, with both whale behavior and regulatory narratives playing a critical role.
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17 Oct 2025
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Matthew Golden player props odds, tips and betting trends for Week 7 | Packers vs. Cardinals – Packers Wire

Player prop bets will be available for Matthew Golden ahead of Sunday’s NFL action at 4:25 p.m. ET live on FOX. The Green Bay Packers (3-1-1) and Golden face off versus the Arizona Cardinals (2-4) in a Week 7 matchup from State Farm Stadium in Glendale, Arizona.
National Football League odds courtesy of BetMGM. Odds updated Thursday at 9:15 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.
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