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Survival for babies born with a birth defect—a 'post-code lottery' – Medical Xpress

             Sign in with                 <a href="https://sciencex.com/profile/sm-login-redirect/fb/" class="login-link" referrerpolicy="unsafe-url">                   <svg>                     <use href="https://medx.b-cdn.net/tmpl/v6/img/svg/sprite.svg#logo_fb" x="0" y="0" />                   </svg>                 </a>                 <a href="https://sciencex.com/profile/sm-login-redirect/google/" class="login-link" referrerpolicy="unsafe-url">                   <svg>                     <use href="https://medx.b-cdn.net/tmpl/v6/img/svg/sprite.svg#logo_google" x="0" y="0" />                   </svg>                 </a>                 <a href="https://sciencex.com/profile/sm-login-redirect/apple/" class="login-link" referrerpolicy="unsafe-url">                   <svg>                     <use href="https://medx.b-cdn.net/tmpl/v6/img/svg/sprite.svg#logo_apple" x="0" y="0" />                   </svg>                 </a>               <br>                 <a href="https://sciencex.com/profile/pwdreset/">Forget Password?</a>               <br>                 <a class="font-weight-normal" href="https://sciencex.com/help/account/">Learn more</a>               <br>share this!<br>Share<br>2<br>Share<br>Email<br>                                                         July 13, 2021                                                                                                              <br>                                           by <a class="article-byline__link" href="http://www.kcl.ac.uk/" target="_blank">King's College London</a>                                  <br>Survival for a baby born with a birth defect—otherwise known as a congenital anomaly—is a "post-code lottery", according to scientists from 74 countries.<br>A study published today in <i>The Lancet</i>, led by researchers from King's College London, examined the risk of mortality for nearly 4000 <a href="https://medicalxpress.com/tags/babies/" rel="tag" class="textTag">babies</a> born with <a href="https://medicalxpress.com/tags/birth+defects/" rel="tag" class="textTag">birth defects</a> in 264 hospitals around the world. The study found babies born with birth defects involving the <a href="https://medicalxpress.com/tags/intestinal+tract/" rel="tag" class="textTag">intestinal tract</a> have a two in five chance of dying in a low-income country compared to one in five in a middle-income country and one in twenty in a high-income country.<br>Gastroschisis, a birth defect where the baby is born with their intestines protruding through a hole by the umbilicus has the greatest difference in mortality with 90% of babies dying in low-income countries compared with 1% in high-income countries. In high-income countries, most of these babies will be able to live a full life without disability.<br>Principal Investigator Dr. Naomi Wright is a Paediatric Surgery Registrar from King's College London who has devoted the last four years to studying these disparities in outcome. She said: "Geography should not determine outcomes for babies who have correctable surgical conditions. The Sustainable Development Goal to 'end <a href="https://medicalxpress.com/tags/preventable+deaths/" rel="tag" class="textTag">preventable deaths</a> in newborns and children under 5 years old by 2030' is unachievable without urgent action to improve <a href="https://medicalxpress.com/tags/surgical+care/" rel="tag" class="textTag">surgical care</a> for newborns in low- and <a href="https://medicalxpress.com/tags/middle-income+countries/" rel="tag" class="textTag">middle-income countries</a>."<br>Mr Andrew Leather, co-author and Director of the King's Centre for Global Health and Health Partnerships at King's College London said: "There needs to be a focus on improving surgical care for newborns in low- and middle-income countries globally. Over the last 25 years, while there has been great success in reducing deaths in children under 5 years by preventing and treating infectious diseases, there has been little focus on improving surgical care for babies and children and indeed the proportion of deaths related to surgical diseases continues to rise.<br>"Birth defects are now the 5th leading cause of death in children under 5 years of age globally, with most deaths occurring in the newborn period. Birth defects involving the intestinal tract have a particularly high mortality in low- and middle-income countries as many are not compatible with life without emergency surgical care after birth."<br>In high-income countries, most women receive an antenatal ultrasound scan to assess for birth defects. If identified, this enables the woman to give <a href="https://medicalxpress.com/tags/birth/" rel="tag" class="textTag">birth</a> in a hospital with children's surgical care so the baby can receive help as soon as it is born. In low- and middle- income countries, babies with these conditions often arrive late to the children's surgical centre in a poor clinical condition. The study shows that babies who present to the children's surgical centre already septic with infection have a higher chance of dying.<br>Co-author Mr Niyi Ade-Ajayi, Paediatric Surgeon at King's College Hospital and Co-Chair of the International Affairs Committee of the British Association of Paediatric Surgeons added: "The study highlights the importance of perioperative care (the care received either side of the corrective operation or procedure) at the children's surgical centre. Babies treated at hospitals without access to ventilation and intravenous nutrition when needed had a higher chance of dying. Furthermore, not having skilled anaesthetic support and not using a surgical safety checklist at the time of operation were associated with a higher chance of death."<br>The team of researchers found that improving survival from these conditions in low- and middle-income countries involves three key elements:<br>1) improving antenatal diagnosis and delivery at a hospital with children's surgical care,<br>2) improving surgical care for babies born in district hospitals, with safe and quick transfer to the children's surgical centre,<br>3) improved perioperative care for babies at the children's surgical centre.<br>They acknowledge that this requires strong teamwork and planning between midwifery and obstetric teams, newborn and paediatric teams, and children's surgical teams at the children's surgical centre, alongside outreach education and networking with referring hospitals.<br>They also urge that alongside local initiatives, surgical care for babies and <a href="https://medicalxpress.com/tags/children/" rel="tag" class="textTag">children</a> needs to be integrated into national and international child health policy and should no longer be neglected within global child health.<br><strong>More information:</strong>                                                     Naomi Jane Wright et al, Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study, <i>The Lancet</i> (2021). DOI: 10.1016/S0140-6736(21)00767-4                                                                                                                                                                                               <div class="mt-3">                                                  <strong>Journal information:</strong>                                                                                                           <a href="https://medicalxpress.com/journals/lancet/"><cite>The Lancet</cite></a>                                                        <a class="icon_open" href="http://www.thelancet.com/journals/lancet/issue/current" target="_blank" rel="nofollow">                                                          <svg>                                                               <use href="https://medx.b-cdn.net/tmpl/v6/img/svg/sprite.svg#icon_open" x="0" y="0"/>                                                            </svg>                                                      </a>                                                                                                    </div>                                                                                          <br>Explore further<br>Facebook<br>Twitter<br>Email<br> Feedback to editors<br>Oct 9, 2025<br><span>0</span><br>Oct 9, 2025<br><span>0</span><br>Oct 8, 2025<br><span>0</span><br>Oct 7, 2025<br><span>0</span><br>Oct 7, 2025<br><span>0</span><br>2 hours ago<br>2 hours ago<br>7 hours ago<br>18 hours ago<br>23 hours ago<br>Oct 10, 2025<br>Oct 10, 2025<br>Oct 10, 2025<br>Oct 10, 2025<br>Oct 10, 2025<br>May 26, 2021<br>Jan 21, 2021<br>Dec 10, 2019<br>Dec 12, 2016<br>Nov 23, 2020<br>Feb 21, 2018<br>Oct 10, 2025<br>Oct 9, 2025<br>Oct 8, 2025<br>Oct 8, 2025<br>Oct 8, 2025<br>Oct 8, 2025<br><br>                                 <small>                                 This summary was automatically generated using LLM.                                  <a class="text-info" href="https://sciencex.com/help/ai-disclaimer/" target="_blank">Full disclaimer</a>                                 </small>                             <br>                                          Use this form if you have come across a typo, inaccuracy or would like to send an edit request for the content on this page.                                            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MoonBull ($MOBU), XRP, ADA – Best Crypto to Buy in October – CoinCentral

XRP and Cardano are maintaining strong market positions, with steady momentum attracting investors’ attention. Amidst this stability, the real buzz is happening with MoonBull ($MOBU) presale. MoonBull shines as the best crypto to buy in October. Early access offers the lowest entry price, exclusive rewards, and a chance to participate in a high-growth project from the ground up. Meanwhile, enthusiasts are closely following Cardano price prediction, staying updated with the latest Cardano news and XRP news to make informed investment decisions.
Every stage brings anticipation, and with Stage 4 underway, the excitement is palpable. This is your opportunity to explore MoonBull ($MOBU)’s innovative features, generous staking, and referral programs, all while securing your position before the next surge. This article will cover the developments and updates of all three coins: MoonBull ($MOBU), XRP (XRP), and Cardano (ADA).
At Stage 10 of the presale, MoonBull ($MOBU) unlocks its high-yield staking program, offering a fixed 95% APY for token holders. Staking is seamless from the dashboard, with rewards calculated daily and a 2-month lock-in period on earned rewards. Investors retain full control over their tokens, with the flexibility to unstake anytime while accumulating impressive passive growth. Funded from a dedicated staking pool of 14.68 $MOBU, this program is designed to encourage long-term holding and increase token stability. There’s no minimum staking requirement, so every holder, small or large, can participate in the growth.

MoonBull ($MOBU)’s referral program incentivizes community growth by rewarding both referrers and invitees instantly. Referrers earn 15% of the total purchase amount of their invitees, while the referred participants receive an additional 15% in $MOBU tokens on top of their purchase.MoonBull leads as the best crypto to buy in October. On top of this, top monthly referrers can earn USDC bonuses of 10% for the top three, and 5% for 4th and 5th place, distributed automatically without any waiting.
Backed by an 11% allocation of $8.05 billion $MOBU, the referral system drives scalable engagement while fostering fairness. Combining staking with this referral program positions MoonBull ($MOBU) as a must-watch for investors seeking community-driven growth and extraordinary returns.
MoonBull ($MOBU) presale is live, and early-stage investors are seizing the opportunity. Currently in Stage 4 for $0.00005168, the presale has already raised over $300,000 with more than 1,000 token holders on board. MoonBull leads as the best crypto to buy in October. Stage 4 investors are looking at a current ROI of 11,800% from Stage 4 to the listing price of $0.00616.
An investment of $10,000 at this stage would yield 193,498,452.01 tokens, potentially converting into $1,191,950.46 at listing. Each presale stage increases by 27.40% until Stage 22, with Stage 23 at 20.38%. The low entry price, combined with exponential growth potential, makes MoonBull ($MOBU) a compelling choice. Don’t miss this moment. Join the presale today and secure your place in what could be the next meme coin phenomenon.
XRP (XRP) continues to hold attention with a current price of $2.80 and a 24-hour trading volume of $5,330,273,825. XRP remains a reliable asset in diversified portfolios due to its strong market fundamentals. Traders are closely monitoring price movements as XRP demonstrates stability and potential for incremental gains.
XRP’s position in the market offers investors confidence, liquidity, and steady returns. Keeping an eye on XRP’s developments remains essential for anyone tracking top-performing cryptocurrencies. Its consistent performance and adoption across platforms make it a reliable choice for both new and seasoned investors.
Cardano (ADA) is currently trading at $0.817200, with a 24-hour trading volume exceeding $1.2 billion, reflecting vigorous market activity. Cardano is known for its focus on scalability, sustainability, and long-term blockchain development, attracting investors seeking robust and reliable networks. Unlike highly volatile meme coins, Cardano’s growth is steadier, offering a balance of innovation and security for strategic investors.
Cardano continues to expand its ecosystem through ongoing technological upgrades, including innovative contract enhancements and platform improvements. Cardano’s adoption and development progress make monitoring and analyzing the Cardano price forecast essential for both short-term traders and long-term holders. Staying informed helps investors make strategic decisions and capitalize on opportunities in the evolving crypto market.

While XRP (XRP) and Cardano (ADA) maintain strong positions in the market, MoonBull ($MOBU) stands apart as the best crypto to buy in October. Its live presale, high-yield staking, and dynamic referral system create a unique investment opportunity with exponential growth potential. Early participation could yield significant rewards, turning strategic investors into substantial beneficiaries of this rising meme coin.
The current Stage 4 presale offers unmatched entry pricing, making it a crucial moment for serious investors to act. With momentum building, MoonBull ($MOBU) shines among the best crypto to buy in October, providing a combination of excitement, innovation, and tangible growth. Don’t let this chance slip. Participate in the presale now and be part of a transformative project.

Website: Visit the Official MOBU Website
Telegram: Join the MOBU Telegram Channel
Twitter: Follow MOBU ON X (Formerly Twitter
MoonBull ($MOBU) is a high-potential meme coin offering staking, referral rewards, and a live presale.
Visit the official MoonBull website, connect your wallet, and purchase $MOBU tokens.
XRP is currently trading at $2.80 with strong market liquidity.
Cardano trades at $0.817200, showing steady growth potential.
MoonBull ($MOBU) presale offers low entry, high ROI, and strong community-driven incentives.
Disclaimer: This media platform provides the content of this article on an “as-is” basis, without any warranties or representations of any kind, express or implied. We assume no responsibility for any inaccuracies, errors, or omissions. We do not assume any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information presented herein. Any concerns, complaints, or copyright issues related to this article should be directed to the content provider mentioned above.
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Crypto.com CEO Urges Regulatory Scrutiny After $19 Billion Liquidations – ForkLog

Regulators should conduct a thorough investigation of cryptocurrency exchanges where traders suffered the most significant losses during a record liquidation exceeding $19 billion, stated Crypto.com CEO Kris Marszalek.
Regulators should look into the exchanges that had most liquidations in the last 24h and conduct a thorough review of fairness of practices. Any of them slowing down to a halt, effectively not allowing people to trade? Were all trades priced correctly and in line with indexes?… pic.twitter.com/UCD6iKuKFQ
— Kris | Crypto.com (@kris) October 11, 2025

He believes oversight bodies should assess the “fairness” of the practices employed by these platforms.
“Did any of them slow down to a complete halt, effectively preventing people from trading? Were all trades priced correctly and in line with indexes? How are trade monitoring and anti-money laundering programs organized?” Marszalek outlined potential questions for the exchanges.
He emphasized that many users were affected during the large-scale position closures, and it is the regulators’ duty to protect consumers and ensure market integrity.
According to CoinGlass, in the past 24 hours, amid the market crash, the liquidation volume reached approximately $19.3 billion. Crypto researcher Quinten François noted that this figure far exceeded those recorded during the COVID-19 pandemic crash ($1.2 billion) and the FTX collapse ($1.6 billion).
Covid crash: $1.2B in liquidations
FTX crash: $1.6B in liquidations
Today: $19.31B in liquidations
You wished you bought during the COVID crash.
This is your COVID crash. pic.twitter.com/OnmNY7e86s
— Quinten | 048.eth (@QuintenFrancois) October 11, 2025

The undisputed leader in forced position closures for the day was the perp-DEX Hyperliquid with a volume of $10.3 billion. Trailing significantly behind were Bybit ($4.6 billion) and Binance ($2.4 billion).
“More than 1,000 wallets on Hyperliquid were completely wiped out in the market crash — users lost everything,” noted Lookonchain experts.
More than 1,000 wallets on #Hyperliquid were completely wiped out in the market crash — losing everything.
In total, 6,300+ wallets are in the red, with combined losses exceeding $1.23B.
205 wallets lost over $1M
1,070+ wallets lost over $100K
Data based on Hyperliquid… pic.twitter.com/pXl6bH8XTc
— Lookonchain (@lookonchain) October 11, 2025

In total, over 6,300 addresses on the platform suffered losses, with their combined damage exceeding $1.23 billion. Losses for 205 traders exceeded $1 million, with the account TheWhiteWhale leading the way — down nearly $61 million. 
“Hyperliquidated” — some commentators played on the exchange’s name.
Binance acknowledged that some liquidations were linked to the temporary loss of peg for three tokens: USDE, BNSOL, and WBETH. The platform’s co-founder Yi He assured that the exchange would compensate for losses incurred due to its fault.
Due to significant market fluctuations over the past 16 hours and a substantial influx of users, some users have encountered issues with their transactions. I deeply apologize for this. If you have incurred losses attributable to Binance, please contact our customer service to… https://t.co/9Q7GZuFY5H
— Yi He (@heyibinance) October 11, 2025

However, losses related to market fluctuations and unrealized profits are not subject to compensation, she emphasized.
“The reason Binance is Binance is that we never shy away from problems. When we fail, we take responsibility — without any excuses or justifications,” He stated.
Aster did not make it into the top 10 platforms by daily liquidation volumes. In recent months, the Binance-backed platform has attracted attention for its rapid growth.
Earlier, the analytical platform DeFi Llama excluded Aster’s trading volume data due to suspicions of manipulation.
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XRP Crashes 40% as Whales Sell Off – Can Ripple’s Token Rally to $4? – ts2.tech

XRP endured a stunning flash crash in early October 2025, underscoring how volatile crypto markets remain. Between Oct. 10–11, XRP’s price plummeted over 40% within hours, a move described as a forced “deleveraging” across trading venues [21]. The token plunged from around $2.80 to as low as $1.64 amid a wave of long position liquidations and stop-loss triggers [22]. Exchange volumes exploded well above normal levels during the rout, indicating many traders were forced out of leveraged bets as XRP collapsed. Large holders (whales) dumping coins were a major factor – whale-induced selling cascades helped make this one of XRP’s worst single-day drops on record [23].
Broader market turmoil compounded the plunge. The crash came as part of a wider crypto sell-off that day, sparked by macro-economic shocks. Notably, an escalation in the U.S.-China trade war – President Trump announcing a sudden 100% tariff on Chinese goods – triggered a market-wide panic on Oct. 10 [24] [25]. Bitcoin dropped over 10%, while major altcoins like ETH, SOL and XRP crashed 20–30% amid a “flash crash” liquidity event [26] [27]. Over $7 billion in crypto long positions were liquidated across exchanges during this turmoil. XRP, already susceptible to large swings, was hit especially hard by this macro-driven shock combined with concentrated whale selling. By the end of that volatile session, XRP had bounced off its lows to around $2.36 [28] – a partial recovery that still left it down double-digits for the day.
Blockchain data confirms that whales amplified the sell-off. In the week leading up to the crash, an estimated 320 million XRP (nearly $950M) was transferred from whale wallets to exchanges [29]. Such large inflows to exchanges are often a precursor to big holders selling. In fact, one huge holder alone dumped 160 million XRP (~$480M) in early October [30], according to TS2.Tech analysis. “Selling pressure persists,” noted CryptoQuant analyst Maartunn, who observed whales moving around $50 million of XRP per day out of their wallets in recent weeks [31]. This steady stream of supply from whales put heavy pressure on XRP’s price and broke the token’s psychological $3 support even before the broader market panic. As XRP slid under $3, a cascade of margin calls ensued – roughly $500 million worth of XRP long positions were liquidated as automated stop-losses kicked in [32].
Crypto analysts warn that concentrated selling by whales can destabilize prices in the near term. Trader CryptoOnchain commented that the on-chain data “strongly suggests whales are positioning for a significant sell-off,” creating “immense selling pressure” and “a high risk of a sharp correction” in XRP’s price [33]. In other words, big players taking profits can quickly turn into a self-fulfilling downturn as other investors panic-sell in response. The recent whale-driven dump has traders eyeing XRP’s support levels nervously. If the $2.75–$2.80 zone (which has acted as support through late September) fails to hold, technical analysts fear a deeper slide could follow [34]. Veteran chartist Peter Brandt even put XRP on his “short candidates” list, warning that a breakdown from XRP’s current descending triangle pattern could send the token spiraling toward $2.20 [35]. “$XRP is on my list of short candidates, but it is conditional upon completing the descending triangle,” Brandt noted, implying that only if XRP loses key support would he expect a drop to those bearish targets [36]. For now, XRP’s bulls are fighting to defend the high-$2 range to prevent further capitulation.
Despite the recent turbulence, a foundational positive development underpins XRP’s longer-term narrative: regulatory clarity. After nearly three years of litigation, Ripple Labs’ courtroom battle with the U.S. Securities and Exchange Commission (SEC) finally concluded in August 2025 with a settlement. Ripple agreed to pay a $125 million fine – but crucially, the settlement affirmed that XRP is not a security when sold in secondary markets [37]. This outcome, building on a pivotal court ruling from 2023, lifted a dark cloud of uncertainty from XRP’s future. It meant that U.S. crypto exchanges and investors no longer had to fear that transacting in XRP might be violating securities laws.
The end of the SEC case was a watershed moment for XRP’s acceptance. Almost immediately after the legal resolution, major American exchanges that had delisted XRP (like Coinbase) relisted the token for trading [38]. With the legal “handcuffs” off, pent-up demand flooded back – investors piled into XRP following the settlement, driving its price sharply higher in mid-2023 and beyond [39]. Over the 12 months leading up to October 2025, XRP rallied roughly 380%, from around $0.60 to the $2.50–$3.00 range [40], in large part thanks to the confidence instilled by Ripple’s courtroom victory. “XRP’s price soared after Ripple survived a lengthy SEC lawsuit,” one investment analysis noted, underscoring how the legal win unleashed XRP’s upside [41].
Regulatory clarity also paved the way for institutional adoption initiatives that were previously on hold. Notably, as soon as XRP’s legal status was clarified, multiple asset managers raced to file proposals for the first U.S. spot XRP exchange-traded funds. By September 2025, at least six firms – including industry heavyweights like Grayscale, WisdomTree, Bitwise, CoinShares, and Franklin Templeton – had submitted applications to launch XRP-backed ETFs [42] [43]. Such products would allow traditional investors (who may not want to hold crypto directly) to gain exposure to XRP via regulated stock-market vehicles. This flurry of filings was directly enabled by the SEC case resolution; as Ripple’s legal counsel Stuart Alderoty quipped, “clarity breeds opportunity.” With the lawsuit behind it, XRP is now free to integrate further into the U.S. financial system. Ripple has even applied for a U.S. national banking charter as of late 2025 [44] – a move that, if approved, could embed XRP more deeply in traditional finance. All told, Ripple’s hard-fought legal victory removed the biggest barrier to mainstream institutional involvement with XRP, setting the stage for the next wave of growth.
The XRP community’s attention is now laser-focused on mid-October 2025, when the SEC will decide on approving spot XRP ETFs – a development many see as a potential game-changer. The deadline window from Oct. 17 to Oct. 25 will see the SEC rule on a batch of high-profile XRP ETF applications [45] [46]. Crypto market watchers are extremely optimistic about approval chances. Bloomberg Intelligence analysts Eric Balchunas and James Seyffart, who track crypto ETFs closely, recently said they assign ~100% probability to a spot XRP ETF getting the green light in this cycle [47] [48]. Prediction markets echo that confidence, pricing in over 95% odds that at least one XRP fund will be approved this month [49] [50]. In other words, virtually everyone expects the SEC to say “yes” to an XRP ETF imminently, especially after recent court victories forced the agency to soften its stance on crypto products.
If an approval does happen, its significance for XRP could be huge. Observers have dubbed the ETF decision a potential “binary event” – a catalyst that could sharply swing XRP’s price either up or down [51] [52]. On the upside, a spot ETF would make it far easier for institutional and retail investors to pour money into XRP through brokerage accounts. “Even one approval could open the floodgates,” bringing a wave of new capital and “turbocharging” prices, analysts say [53]. Some predict that pent-up institutional demand (from crypto funds, hedge funds, etc.) could immediately add billions of dollars of buying pressure for XRP if an ETF launches [54]. It’s no surprise then that sentiment is growing euphoric ahead of the decision. “Buckle up! XRP to $5 seems fair,” one market commentator quipped, reflecting a view that an ETF blessing might send XRP skyrocketing toward the $5 mark in short order [55]. The mere anticipation of approval has likely contributed to XRP’s resilience around the $2.80 level recently, as traders position ahead of the news.
Of course, there is a downside scenario: if the SEC were to deny or delay the XRP ETFs, it could deal a short-term blow to market sentiment. XRP’s price already wobbled in early October on (false) rumors of an ETF delay, briefly dipping below $3 on that scare [56]. A real denial could trigger disappointment selling, given how much optimism is currently baked in. However, most experts view outright rejection as unlikely now – especially since the SEC has been approving similar crypto products (e.g. Ethereum futures ETFs) and has shown signs of warming up post-Ripple lawsuit [57]. There was a brief complication when a U.S. government shutdown in early October threatened to pause SEC processes, but with the government running, regulators are expected to stick to the late-October timeline [58]. In addition to the ETF decision, Ripple’s own initiatives are on the horizon: the company expects feedback on its pending bank charter by the end of October [59], and it continues rolling out new products like a dollar-backed stablecoin RLUSD on the XRP Ledger [60]. Even former U.S. President Donald Trump unexpectedly gave XRP a nod – meeting with Ripple’s CEO and later musing about “upgrading the ancient financial system” with crypto, which speculators took as a sign of potentially friendlier policy ahead [61]. All these brewing factors make mid-to-late October a pivotal period. If ETFs and licenses get approved, XRP could see a significant sentiment boost; if not, the asset may remain range-bound or even pull back as the hype unwinds. In short, “Uptober” 2025 isn’t over yet for XRP – the biggest news may still be to come in the next couple of weeks.
While traders fixate on short-term price swings, it’s worth noting that XRP’s fundamentals have been improving. Ripple’s core mission is to drive adoption of XRP as a bridge currency for cross-border payments, and 2025 has seen real progress on that front. The company’s flagship product, On-Demand Liquidity (ODL), uses XRP to enable instant international money transfers. By this year, ODL has gained solid traction with banks and fintechs worldwide. The XRP Ledger’s usage has skyrocketed – by early 2025 it was processing over 2 million transactions per day, ranking among the most active blockchains [62]. Major financial institutions such as Santander and SBI Remit (Japan) have piloted or expanded services using XRP for remittances [63]. In fact, an estimated $1.1 billion in XRP was purchased by institutions in 2025 specifically for use in Ripple’s payment network [64] – a sign that big players are acquiring XRP not just to speculate, but to utilize it. This kind of organic demand provides a fundamental “floor” under XRP’s value. Even during price dips, Ripple’s partners still need liquidity (XRP) to facilitate transfers, which can help buffer extreme downswings. Ripple’s push into central bank partnerships and possibly a banking license could further entrench XRP in the plumbing of global finance. These developments suggest XRP is gradually evolving from a purely speculative asset into a utility token with a growing base of end-users.
Macro-economic conditions may also start tilting in XRP’s favor looking ahead. The narrative of late 2025 is shifting from monetary tightening to easing – interest rates are expected to peak and potentially decline going into 2026, which could renew investor appetite for risk assets like crypto [65]. “Favorable monetary conditions – lower interest rates on the horizon and abundant liquidity – have been a key support for crypto prices,” as one analysis noted [66]. In 2024–2025, the Federal Reserve’s rate hikes and a strong U.S. dollar created headwinds for crypto, but now markets are betting on Fed rate cuts in Q4 2025 due to cooling inflation [67] [68]. Easier money and a “risk-on” environment historically benefit cryptocurrencies. Additionally, the total crypto market cap recently swelled above $4 trillion during the “Uptober” rally [69], indicating broad capital inflows into the space. Bitcoin’s surge to a new all-time high (~$125K) this month lifted sentiment across the board [70]. Although XRP lagged Bitcoin and Ether’s breakout (partly due to lacking an approved ETF, as analysts noted) [71], it still rode the positive wave – at one point reclaiming its spot as the #3 crypto by market cap [72]. This environment of improving sentiment, plus hints of pro-crypto regulatory shifts (like the EU’s MiCA framework and even U.S. political figures warming to crypto), sets a constructive backdrop for XRP going forward. As long as whales don’t completely sour the mood, XRP appears well-positioned fundamentally: it has legal clarity, increasing real-world use, and potential institutional catalysts on deck.
After such a dramatic crash and rebound, what comes next for XRP’s price? Experts are divided in their predictions, but most see October 2025 as a turning point. Bullish analysts argue that the ingredients are in place for another major XRP rally, provided key hurdles are cleared. One optimistic scenario posits that if XRP can break above its late-August high around $3.30, there’s little technical resistance until the mid-$5 range [73]. Chart analysts note that XRP failed to breach $3.30 during the recent run-up; moving decisively past that level could ignite fresh momentum. In fact, some technicians say above ~$3.30, XRP could sprint toward $5–$8 relatively quickly in a euphoric market, given the lack of historical selling zones in that gap [74] [75]. Looking further out, many forecasters still see upside within the next year. The Motley Fool’s Leo Sun, for example, points to Ripple’s legal win and growing utility as reasons XRP could be worth around $4 in 12 months [76]. A Finder.com panel of fintech experts offered a more modest average projection of about $3.00 by end-2025, essentially flat from current levels [77], but that assumed no big catalyst. Should an ETF launch and spur new investment, even traditional banks have rosy outlooks – Standard Chartered researchers reportedly think XRP can reach $5+ by December 2025 in a strong adoption scenario [78] [79]. Some crypto fund strategists have floated specific targets (one NASDAQ market commentator predicted roughly $5.90 within three years for XRP under favorable conditions) [80]. The bullish thesis centers on the idea that institutional inflows and broader usage could drive XRP to new multi-year highs beyond the $3.84 peak from 2018.
On the other hand, bearish or cautious analysts urge not to get carried away. They emphasize that XRP remains in a precarious spot until it proves the recent sell-off is fully behind it. The immediate support to watch is around $2.75–$2.80 – a region that has held through the latest volatility. If XRP decisively breaks below that floor, it would signal fading bullish momentum and could invite another leg down [81]. As noted, veteran trader Peter Brandt identifies a large descending triangle pattern on the charts (lower highs against a flat base) that could resolve violently downward. Brandt warns that a breakdown under roughly $2.64 could trigger a drop to ~$2.20 [82], which would erase much of 2025’s gains. In his view, XRP hasn’t negated that bearish setup yet, so the risk remains. Many traders similarly agree that as long as XRP languishes under its $3.30 resistance and keeps making lower highs, the bulls are not firmly back in control [83]. In the near term, consolidation in the high-$2s suggests a neutral stance – neither side has a clear edge while the market awaits the coming news. “A relief bounce alone isn’t enough – bulls must reclaim higher levels to regain momentum,” one analyst remarked [84], reflecting the cautious optimism among XRP watchers. Essentially, XRP is at a crossroads: positive breakthroughs (ETF approval, major partnerships, a supportive macro cycle) could send it rallying toward the $4–$5 range in coming months, but absent those, the token may struggle and remain vulnerable to downside if whales continue to unload.
As of mid-October 2025, XRP is trading around $2.80 per coin [85], roughly unchanged from a day ago as it stabilizes after the recent shock. That price gives XRP a market capitalization near $150 billion, solidifying it as the world’s #3 cryptocurrency by value behind Bitcoin and Ethereum [86]. Even after the roller coaster, XRP is up approximately 35–40% year-to-date and an astonishing 440% higher than this time last year (when it hovered near $0.50) [87] [88]. Long-term holders who endured the past bear market have seen fortunes improve dramatically. Now the question is whether XRP’s comeback can continue into 2026. The coming days will likely be decisive – regulatory decisions and whale activity will either validate the optimism or reinforce the risks. If XRP’s fundamentals and newfound Wall Street interest carry the day, the token could be on track to approach the $4–$5 range that once seemed far-fetched. If not, traders may be in for more whiplash. Either way, XRP’s next chapter is set to be a defining one, with billions on the line and the world watching closely.
Sources: CoinDesk [89] [90]; TipRanks [91] [92] [93] [94]; TS2.Tech [95] [96] [97] [98]; Motley Fool via Yahoo [99]; Reuters [100].
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A technology and finance expert writing for TS2.tech. He analyzes developments in satellites, telecommunications, and artificial intelligence, with a focus on their impact on global markets. Author of industry reports and market commentary, often cited in tech and business media. Passionate about innovation and the digital economy.
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Navigating the Crypto Storm with Bitcoin and AlphaPepe – OneSafe

Bitcoin’s value swings are more than mere financial blips; they are tumultuous waves crashing against the shores of investor confidence. In this unsteady climate, a novel contender, AlphaPepe, springs forth as a beacon amidst the turmoil of a meme coin revolution.
With cryptic discussions fluttering about Bitcoin plummeting to the $60,000 mark, astute investors are veering their gaze toward the vibrant realm of meme currencies. This piece delves into the current state of Bitcoin’s volatile market, reflects on its repercussions, and reveals how AlphaPepe is carving out its niche as a premier presale opportunity in this chaotic environment.
Bitcoin, often synonymous with erratic price movements, possesses a magnetic pull on the imaginative investor. The unsettling forecast of a potential downturn to $60,000 serves as more than just chatter; it represents a crucial crossroads before embarking on a renewed bull market. History suggests that such corrections spark a renewed interest in alternative cryptocurrencies and whimsical meme projects, like AlphaPepe, all of which find themselves in the spotlight once again.
While such fluctuations might stir anxiety for some, others see them as gateways to unmatched opportunities. As dominant cryptocurrencies gradually stabilize, keen participants are looking toward novel assets bursting with promise. The evolving relationship between Bitcoin’s established standing and the meteoric rise of meme coins is reshaping investment strategies, creating a rich tapestry of potential.
Contrasting the security that Bitcoin often provides to institutional backers, retail investors are increasingly enamored by the thrilling prospects offered by presales like AlphaPepe. Nestled on the BNB Chain, AlphaPepe artfully marries meme culture’s excitement with sustainable tokenomics, boasting instant token delivery alongside a stellar staking protocol that can yield returns upwards of 85% APR.
With over $295,000 raised during its presale and a burgeoning base of thousand holders, AlphaPepe is catching fire. The engagement levels within its USDT liquidity pools reflect an encouraging grassroots movement, propelling it into prime position as a favorite among retail investors.
As Bitcoin wades cautiously through the unpredictable waters of the market, enthusiasm around meme coins has surged dramatically. Retail traders are increasingly on the hunt for assets that could outpace traditional returns, breaking free from the constraints of mundane investments. Analysts note that past cycles have witnessed explosive upsurges in meme coins, with current market sentiment hinting at a similar fate for projects like AlphaPepe.
With the future of Bitcoin still mired in speculation, investors are recognizing the importance of diversifying their portfolios to include high-potential overlay assets. In this environment, AlphaPepe stands out—as an alluring investment option that balances forward-looking speculation with a sound foundation.
Investors today are becoming increasingly savvy, realizing the necessity of a dual strategy. While Bitcoin fortifies the portfolio with a sense of security and institutional credibility, AlphaPepe embodies the exhilarating potential of high-risk, high-reward investments. This blending of Bitcoin’s steadfastness with AlphaPepe’s flair for speculation empowers traders to maximize the inherent volatility of cryptocurrencies.
Never has this approach been more critical, especially as financial markets grapple to provide explosive returns amid uncertain times. In its nascent trading journey, AlphaPepe is riding the tide of rising retail speculation. Keep an eye on this project, as it stands poised for an intriguing ascent towards 2025 and beyond.
What sets AlphaPepe apart in the crowded cryptocurrency landscape is its commitment to transparency. With an audited smart contract and guaranteed liquidity, these features work to assuage the typical concerns many investors may harbor. They help to establish AlphaPepe’s reputation, especially in a field often plagued by scams and insecurity.
This emphasis on accountability communicates a significant message: meme coins can yield lasting growth when community engagement intersects with conscientious management. Investors can rest assured that beneath AlphaPepe’s playful exterior lies a robust structure designed for sustainable trust and longevity.
As Bitcoin wrestles with its relentless price swings, innovative projects like AlphaPepe capture the imaginations of a broader spectrum of investors through strategic presale initiatives and community engagement. The complex interplay between Bitcoin’s volatility and the thriving meme coin market is undeniably reshaping the investment landscape, challenging established practices.
As the cryptocurrency ecosystem evolves, it’s crucial for investors to stay alert and adaptable, constantly scouting opportunities that promise impressive returns. The future might just belong to both the steadfast Bitcoin and the exhilarating AlphaPepe, heralding an era marked by diversification and resilience in investment strategies.

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Top Crypto Coins Showdown: Why BlockDAG, XRP, Stellar & Chainlink Are Winning Attention in Q4! – CoinCentral

As people look beyond quick market swings toward lasting digital value, a major question stands out: which are the top crypto coins shaping the future? It’s no longer just about tech strength but about projects that build strong use cases, connect with communities, and make a mark in real-world settings.
Stellar continues to power cross-border systems, Chainlink drives oracle connections, and XRP gains attention as regulations ease. Yet one name is setting records for both visibility and real use: BlockDAG. With nearly $420 million raised, a global Formula 1® tie-up, and a ready-to-scale system, BlockDAG is not just talking progress, it’s showing it.
BlockDAG’s partnership with the BWT Alpine Formula 1® Team stands out as one of the boldest moves in recent crypto history. Rather than chasing short-term fame through simple sponsorships, BlockDAG (BDAG) connects its Layer 1 network with real activities, from blockchain-powered simulators to developer hackathons and live tech showcases.
So far, BlockDAG has gathered more than $420 million and sold nearly 27 billion BDAG coins, yet the best part remains: the coin’s limited-time price is only $0.0018, while the standard Batch 31 price sits at $0.0304. This steep difference highlights how early participants still have access to a rare entry level before the next phase.
The much-awaited Genesis Day on November 23 will spotlight live applications, BDAG tools, and international broadcasts to mark its progress. These milestones make BlockDAG not only one of the top crypto coins but also one of the most community-driven names in the market today.
While other coins continue to plan features, BlockDAG is rolling out working utilities linked to fan engagement, something few have achieved in the crypto scene.
With over 20K miners, 312K+ BDAG holders, and 3M+ X1 users, the project shows wide participation and enthusiasm. By connecting culture, tech, and real events, BlockDAG is turning visibility into tangible impact, proof of why it stands at the top of this race.
Stellar (XLM) built its name around low-cost global transfers, creating reliable pathways for remittances and financial institutions. Its network once promised to reshape traditional systems like SWIFT, and for a time, adoption was steady. Lately, however, its momentum has softened as competition grows and use cases plateau.
While BlockDAG expands into real-world interaction, Stellar remains focused mainly on the technical side. It still holds market trust, but its visibility among newer participants is limited. Without stronger outreach to everyday users, Stellar risks staying a background player while more active projects like BlockDAG continue to attract wider attention.
Chainlink (LINK) remains unmatched in its ability to supply accurate data for decentralized systems. Its partnerships with major platforms make it an essential part of DeFi and traditional finance integrations.
Many analysts still list LINK as a reliable choice for 2025 due to its established presence in digital infrastructure. Even so, Chainlink’s success depends mostly on business-to-business growth and technical adoption. Its focus is on back-end operations rather than public visibility.
While it’s linked with hundreds of protocols, it doesn’t engage mass audiences the way BlockDAG does through events like its Alpine F1® initiative. For those seeking a mix of community energy and functional depth, BlockDAG presents a broader approach that bridges both.
XRP has been regaining attention as liquidity conditions improve and court outcomes begin to shift in its favor. The project could reclaim a top-three market position once legal clarity arrives and Ripple deepens its banking partnerships across more regions. Its fast transaction speeds and long-standing institutional use remain major strengths.
However, XRP’s legal hurdles still cloud its long-term stability for retail holders. While progress continues, uncertainty keeps limiting its full recovery. On the other hand, BlockDAG has already achieved full compliance while forming recognized partnerships that extend across global platforms, giving it a more secure and relatable standing.
Each of the well-known names, Stellar, Chainlink, and XRP, maintains relevance through clear utility and specialized infrastructure. But BlockDAG is changing how people see value in digital assets. It is not just building systems; it is merging use, community, and visibility to create a lasting presence.
With nearly $420 million raised, nearly 27 billion coins sold, and a 2,940% rise since Batch 1, BlockDAG’s growth outshines most presales ever recorded. The special entry offer of $0.0018 per coin remains available for only a short time before it reaches its regular Batch 31 rate of $0.0304.
For anyone exploring the top crypto coins for the future, BlockDAG stands as the one leading both adoption and attention. Its mix of cultural reach and strong utility gives it an edge few can match, securing its place as a standout project shaping the next phase of digital growth.
Disclaimer: This media platform provides the content of this article on an “as-is” basis, without any warranties or representations of any kind, express or implied. We assume no responsibility for any inaccuracies, errors, or omissions. We do not assume any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information presented herein. Any concerns, complaints, or copyright issues related to this article should be directed to the content provider mentioned above.

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What Does the Future Hold for Ripple and XRP Following Ripple’s CTO Exit? Key Players Debate – ZyCrypto

David Schwartz, Ripple’s long-serving Chief Technology Officer, is preparing to step away from his post at the end of 2025, closing out more than a decade at the company he helped shape.
Schwartz reflected on his 40-year career in technology, from early consulting work with the NSA to building the XRP Ledger alongside Ripple’s founders. He described his 13 years at Ripple as “one of the greatest honors and experiences” of his life, second only to his family.
Though leaving day-to-day duties, Schwartz won’t be disappearing from the scene. He will remain involved as “CTO Emeritus” and has accepted a seat on Ripple’s Board of Directors. He also hinted at a return to hands-on development, saying he plans to run his own XRPL node and explore new use cases for the token outside Ripple’s core business.
The announcement comes as XRP trades through a delicate stretch. On September 30, the token closed at $2.84, notching a modest 2% daily gain but still down nearly 4% over the week.
Analysts note that XRP has been holding the $2.80 level as key support. According to market strategist Ali Martinez, if the coin maintains that floor, there are “no major supply walls” preventing a push higher. Technical signals point to a potential breakout toward $3.20, with some traders eyeing $3.80 in the short term.
Meanwhile, on-chain data showed whales accumulating roughly 250 million XRP within a 48-hour window. The bulk purchases have sparked talk of an impending supply squeeze, especially as institutions continue to build positions following Ripple’s EVM sidechain upgrade and rising ETF anticipation.
As Schwartz transitions into a more advisory role, Ripple’s long-term direction will fall increasingly on its next generation of leaders. For XRP, much of its near-term outlook appears tied to whether it can hold its current support levels and capitalize on institutional momentum.

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'XRP Going Nowhere': XRP Ledger Validator Reacts as Crazy Volatility Hits Market – TradingView

Friday saw crypto's worst liquidation as a crazy volatility bout ripped through the market, triggering one of the largest declines in prices of XRP, BTC, ETH and other digital assets seen all year.
XRP fell as much as 42% in Friday’s session, its sharpest one-day drop in the recent year. The sell-off drove XRP's price as low as $1.77 from a high of $2.83 before slightly rebounding.
The price of XRP steadily declined from a high of $3.10 on Oct. 2. Although the drop was punctuated with slight rises, bears gained an upper hand on Friday, crashing XRP's price to a low of $1.77, last seen in April 2025. As reported, multiple death cross signals had appeared on XRP's short-term charts (the one-, two-, three- and four-hour charts), preceding the massive drop.
The price of XRP still seems to be in the woods; at the time of writing, XRP was trading in red, down 14% in the last 24 hours and 19% weekly to $2.44. The drop has pushed XRP lower in crypto rankings, currently the fifth largest with a market valuation of $146.73 billion.
XRP going nowhere
Coinbase director, Conor Grogan, stated that the recent market drop marks the "worst altcoin flashcrash" he has ever seen across the board.
In the last 24 hours, $19.38 billion has been liquidated across digital assets, according to CoinGlass data. Bitcoin accounted for $5.38 billion of this figure, while altcoins accounted for a massive $14 billion.
Be assured, XRP and the XRP Ledger isn't going anywhere.
Volatility is part of the journey. So if you can't stomach it it's ok to step back for a bit.
❤️
Reacting to the crazy volatility seen in the crypto market, XRPL dUNL validator Vet says XRP isn't going anywhere.
"Be assured, XRP and the XRP Ledger isn't going anywhere. Volatility is part of the journey," Vet wrote in a tweet.
Amid the market volatility, Ethena's USDE, BNSOL and WBETH saw a price depeg, which caused forced liquidations in positions.
Ripple USD stablecoin (RLUSD) faced its first stress test in the market since its launch in December 2024. RLUSD rather held up strong, maintaining its USD peg amid the market crash.
Select market data provided by ICE Data Services. Select reference data provided by FactSet. Copyright © 2025 FactSet Research Systems Inc.Copyright © 2025, American Bankers Association. CUSIP Database provided by FactSet Research Systems Inc. All rights reserved. SEC fillings and other documents provided by Quartr.© 2025 TradingView, Inc.

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