Category: Crypto Hub

The crypto market is still active and investors are in search of the best crypto to invest in at the moment. Most investors are focusing on networks that have higher settlements, scalable infrastructure, and actual utility. Because of this, many investors are moving beyond familiar names to also consider newer projects.
Although the big names still influence overall market mood, several smaller and mid-tier networks are starting to pull ahead in ways that actually show up in user activity, development updates, and real demand. Analysts tracking these shifts have been pointing to a select group of altcoins that seem built for the long run, not just the next price swing
From that group, five stand out right now for their mix of usefulness, speed, and steady progress. Remittix (RTX) sits at the front, gaining momentum as a PayFi solution changing how money moves across borders. Following closely are Algorand, Stellar (XLM), Cardano, and XRP, which have strengths that fit the direction in which the market seems to be moving.
Algorand has become a frontrunner in the field of blockchain technology today with a price of about $0.154 specifically because of its focus on scalability, sustainability, and conformity to regulations. Algorand is another technology that has recently caused a commotion after establishing a strategic partnership with Noah with the aim of integrating conventional banking systems with blockchain-based innovations. The step makes Algorand a performance and environmentally friendly blockchain enterprise solution.

With increasing interest from institutional investors and a growing adoption of smart contracts, Algorand offers potential. As the network continues to grow, analysts predict that Algorand could see significant price increases, with some speculating it could hit $2.50 to $3.00 in the medium term.

The project has already sold more than 685 million tokens, raising over 28.1 million dollars and selling the tokens at 0.1166 apiece. Its emphasis on transforming cross-border payments makes it one of the best crypto investments to make in 2025.
The DeFi project is accelerating and is especially the beta wallet which is already operational with positive responses being received by the early testers. Remittix is providing a solution to the problem of making real-world payments by enabling people to make remittances across the globe with its ability to support crypto-to-fiat transfers in more than 30 countries.
The project has recently achieved a Skynet score of 80.09, ranking it #1 on CertiK’s Pre-Launch leaderboard, a clear testament to its security and community trust. As the world of DeFi continues to evolve, Remittix stands at the forefront of blockchain technology innovation, particularly in global payments. With major CEX listings already announced on and more to come, Remittix is poised for significant growth in 2025 and beyond.
XLM, with a price of approximately $0.251, is indicating good growth, owing to its strengthening ties with institutional participants. Stellar has also collaborated with Turbo Energy and Taurus to tokenize renewable-energy debt instruments, which can create a massive shift in the use of blockchain in the financial sector. Stellar’s cross-border payment solutions and focus on DeFi are attracting attention, as well as its partnership with Taurus to build blockchain-based financial products for the future.

As a result, XLM is on many analysts’ lists as one of the best altcoins to buy. Stellar’s regulatory compliance and focus on cross-chain functionality make it a standout in the competitive blockchain space. Analysts are predicting that XLM could potentially rise to $2.50, $4, and even $8, fueled by its real-world utility and solid partnerships.
ADA is priced at $0.464 and has been showing signs of bullish divergence on its RSI indicator. With strong institutional interest and an active development community, Cardano is positioned for a significant push if it maintains support above the $0.45 level. Analysts predict that Cardano could see a rally toward the $0.50-$0.52 level, and further price appreciation could bring the asset to as high as $1.20-$2.00.

The Cardano network has been gaining ground in DeFi with increased focus on staking and smart contract deployment. The network’s unique approach to scalability and sustainability has made it a favorite among crypto investors looking for a project with strong fundamentals. Additionally, Cardano’s ongoing development and plans have analysts optimistic about its long-term potential, with some predicting a 3,000% rally from the current levels..
XRP is among the best crypto to buy in 2025 that is trading at around $1.99. In recent weeks, the price of XRP has been stressed, yet analysts believe that this digital currency has long-term growth prospects, particularly with the upcoming release of the ETF. It is a major milestone to the XRP as this ETF will be listed on the New York Stock Exchange and it is likely to trigger more adoption.

The XRP community is also active, and the on-chain and social volume are increasing. Analysts have given important support levels between 2.00 and 2.06 and should XRP be able to break 2.30, the next level may be 3.82 and 5.17. The limited number of XRP tokens in the market, as well as the increased institutional demand, has made XRP one of the most interesting investments in the crypto sector today. The introduction of XRP ETF may become the trigger that will cause its next significant price growth.

Although the above-mentioned altcoins are promising with their potential, Remittix is the best crypto to purchase now to those who seek real utility, security, and long-term growth opportunity. The cross-border payment solutions of the project and the focus on DeFi make it a unique project in the overcrowded cryptocurrency market. With actual products live, CEX listings, and a growing community behind it, Remittix is set to be a major player in 2025 and beyond.
Discover the future of PayFi with Remittix by checking out their project here:
Website: https://remittix.io/
Socials: https://linktr.ee/remittix
$250K Giveaway: https://gleam.io/competitions/nz84L-250000-remittix-giveaway
1. Should one invest in crypto now?
Yes, it is now a good time to invest in crypto, particularly as we are witnessing a transition to those projects that have practical use and potential to appreciate over time. When seeking investment, one should seek technologies that are not only solid on paper but also on practical applications.
2. What is the future of the next crypto bull market?
Analysts remain optimistic about altcoins that have practical applications, including Remittix and XLM, both of which are set to expand tremendously in the year 2025 and beyond.
3. Which aspects or variables affect crypto prices?
Market conditioning, institutionalization, regulatory developments, and technological change, such as crypto-to-fiat innovations by Remittix, can have a very strong impact on prices
4. Which industries are thriving in the crypto mania?
The most strength is currently being exhibited by DeFi, Layer 2 solutions, and payment networks, with Remittix taking center stage in the cross-border payments industry.
5. What crypto trends are to be monitored by investors?
Monitor more and more people using crypto-to-fiat solutions, as Remittix has been doing, and institutional engagement in major projects such as XRP and Cardano. The two may be combined to enable investors to be ahead of the market.
Disclaimer:
This article is for informational purposes only and does not constitute financial advice. Cryptocurrency investments carry risk, including total loss of capital. Readers should conduct independent research and consult licensed advisors before making any financial decisions.
This publication is strictly informational and does not promote or solicit investment in any digital asset
All market analysis and token data are for informational purposes only and do not constitute financial advice. Readers should conduct independent research and consult licensed advisors before investing.
Crypto Press Release Distribution by BTCPressWire.com
COMTEX_470465368/2909/2025-11-22T13:24:38

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Home – Crypto Presales – $201M SOL Dump: Is Solana Price Prediction Heading Toward $120? Stellar Surges as Apeing Whitelist Opens 10,000% ROI Opportunity
A $201 million SOL dump just hit the market, raising questions about the Solana price prediction and whether it could slide toward $120. Meanwhile, Apeing ($APEING) is preparing a whitelist that gives early participants a chance to secure tokens at the lowest tier, offering potential high returns for those who act fast. For crypto enthusiasts, financial analysts, and developers, this could be one of those rare moments to get in before the wider market reacts.

At the same time, Stellar (XLM) is showing notable gains, highlighting its growing presence in cross-border payments and decentralized finance. With fast transactions, low fees, and expanding adoption, Stellar continues to attract attention from investors and developers looking for reliable blockchain solutions. Its practical use cases make it a strong contender in the evolving crypto landscape.
Apeing ($APEING) is an emerging cryptocurrency designed for early movers looking to get in on a promising new project. Unlike established tokens, Apeing is still building its community and ecosystem, giving investors a chance to secure early access before wider distribution. The project focuses on speed, accessibility, and rewarding those who act decisively, making it ideal for traders who thrive in high-risk, high-reward opportunities.

The token is structured to offer significant upside for early participants, with whitelist members gaining priority access to the initial allocation. While still new, Apeing is already attracting attention from crypto enthusiasts and degen communities for its potential to deliver strong returns. For anyone interested in a fresh, action-oriented crypto project, $APEING presents a chance to join a community-driven token with ambitious growth prospects.
A $201 million SOL dump recently hit the market, stirring concerns about the Solana price prediction and whether the token could drop toward $120. Large sell-offs like this put immediate pressure on the market, especially with upcoming token unlocks and ongoing whale activity. Traders, developers, and analysts are closely watching the price action, as staking rates and transaction activity will play a critical role in stabilizing SOL in the short term.
Despite the volatility, Solana’s network fundamentals remain strong. Its fast transaction speeds, low fees, and growing ecosystem of decentralized applications continue to attract developers and users. While the market reacts to large dumps, SOL’s long-term prospects depend on network adoption and staking participation, making it a token that’s worth monitoring closely for both short-term moves and potential recovery.
Stellar (XLM) is a blockchain platform designed to make financial transactions faster, cheaper, and more secure, particularly for cross-border payments. Unlike traditional banking systems that can take days and charge high fees for international transfers, Stellar enables near-instantaneous transactions with minimal costs. Its unique consensus protocol ensures both speed and reliability, making it a favorite among fintech startups, payment providers, and institutions looking to streamline global transactions.
Beyond payments, Stellar focuses on financial inclusion by connecting unbanked populations to digital financial services. Its decentralized network allows anyone with an internet connection to participate, send, and receive money globally without relying on traditional intermediaries. With growing adoption and partnerships in the fintech space, Stellar is positioning itself as a practical, real-world blockchain solution rather than just another speculative asset, giving investors and developers reasons to watch XLM closely.
Whitelist members get exclusive access to secure $APEING tokens at $0.001 once the first stage begins.
Early movers can secure a 10,000% potential ROI, putting them ahead of late entrants.
History shows that those who act decisively in early-stage coins often reap the largest rewards.
Apeing is community-driven, giving token holders a say in project development and updates.
With a limited whitelist, scarcity boosts demand, making early access crucial for maximum gains.
Here’s the simple route to get in early:
Go to the official $APEING website.
Enter your email in the whitelist section.
Get confirmation via email.
Whitelist members will gain exclusive access to secure Apeing tokens at the earliest pricing stage. Skipping this could mean missing one of the most talked-about early-stage opportunities of the year.

Crypto rewards boldness. Between Solana’s whale dumps and Stellar’s surprising rise, the market is giving a clear signal: those who act decisively could profit, while the hesitant risk being left behind. Apeing represents that opportunity for the bold, early access, extreme upside potential, and a token built for instinctual, action-oriented participants.
For SOL, the Solana price prediction is a rollercoaster: short-term volatility may sting, but strategic moves and staking participation can stabilize long-term growth. In the end, in crypto, only those who APE and HODL consistently emerge ahead. 

Website: Visit the Official Apeing Website
Telegram: Join the Apeing Telegram Channel
Twitter: Follow Apeing ON X (Formerly Twitter)
Solana price prediction depends on market movements, staking participation, and whale activity. Analysts suggest SOL could range between $120 in a worst-case scenario and $200 in bullish conditions. Large dumps and token unlocks could pressure prices in the short term, while staking and ecosystem growth may stabilize long-term value.
To join the Apeing whitelist, visit the official website, enter your email in the whitelist section, submit, and confirm via email. Early whitelist members secure access to the lowest pricing tier and potential high ROI before public distribution.
Apeing is designed for early-stage investors and degen traders. It features community-driven governance, tokenomics that reward long-term holders, and a limited whitelist that increases scarcity. Early participants can benefit from exclusive perks and maximum upside potential.
Solana faces a $201M market dump, raising concerns for the solana price prediction with a potential $120 downside. Meanwhile, Stellar surges, and Apeing ($APEING) launches a whitelist offering early access and a 10,000% ROI potential. Whales, staking, and ecosystem growth shape SOL’s short- and long-term outlook. Apeing targets bold, action-oriented investors, rewarding those who move decisively. This article guides crypto enthusiasts, developers, and analysts through market dynamics, risks, and high-potential opportunities, emphasizing strategy, timing, and early entry.
This article contains information about a cryptocurrency presale. Crypto Economy is not associated with the project. As with any initiative within the crypto ecosystem, we encourage users to do their own research before participating, carefully considering both the potential and the risks involved. This content is for informational purposes only and does not constitute investment advice. 
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In 2025, the 730-day Simple Moving Average (SMA) has become a focal point for many in the crypto space. This indicator has historically marked significant shifts in Bitcoin’s price, and it continues to be relevant today. Notably, Bitcoin’s current trading price of around $85,143.70 is just above the SMA’s critical level of $81,250.86. Past data suggests that when Bitcoin’s price breaches this level, significant market downturns often follow. The cycles we’ve seen since 2014 have shown drops ranging from 77% to 85% post-breach.
Organizations managing crypto assets must pay attention to this indicator, especially if they’re considering crypto mass payouts.
There’s a clear connection between Bitcoin’s price fluctuations and the 730-day SMA. Historical data reveals that each bear market’s onset often coincides with a breach of this SMA. The Glassnode-sourced “Bitcoin Investor Tool” illustrates this relationship well. Past market corrections have been triggered by falling below this moving average, indicating a loss of momentum following euphoric price rallies.
For those managing crypto assets, it’s crucial to understand these cycles. This knowledge can inform decisions about risk exposure and asset allocation, particularly when contemplating crypto mass payouts.
As the crypto landscape evolves, stablecoin salaries are gaining traction in payroll strategies. When Bitcoin’s volatility is a concern, stablecoins—pegged to fiat currencies—offer a more stable alternative. Companies adopting stablecoin salaries can provide employees with consistent income, reducing financial stress.
This trend is especially relevant for startups facing economic uncertainty. In Argentina, where inflation is rampant, startups are increasingly turning to stablecoin salaries as a viable option.
Organizations need to develop strategies to address the volatility associated with crypto salaries. A hybrid payroll model that allows employees to choose between Bitcoin, stablecoins, or fiat currency could balance growth potential and stability. Converting Bitcoin to stablecoins upon receipt can mitigate volatility risk, ensuring payroll costs remain predictable.
Using blockchain platforms for low fees and fast settlements can enhance operational efficiency while navigating the complexities of crypto payments.
The rise of stablecoin salaries allows companies to better withstand market fluctuations, preserving treasury value and providing more stability. As the cryptocurrency market evolves, traditional indicators like the 730-day SMA combined with modern payroll solutions will be crucial in navigating volatility. By embracing these trends, companies position themselves for long-term success in crypto asset management.
In short, the 730-day SMA is still a vital indicator for Bitcoin’s market trends, and the rise of stablecoin salaries is reshaping payroll strategies. Together, they form a framework for organizations to thrive amid the challenges of the cryptocurrency landscape.

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Zcash's privacy features are attracting Bitcoin maxis, reshaping crypto payroll solutions for SMEs. Can ZEC reach $1,000? Explore the future of privacy coins.
Bitcoin hovers above its 730-day SMA, facing a pivotal market moment influenced by historical patterns and ETF inflows. Explore insights into its potential price trajectory.
Understand the risks of investing in Bitcoin Munari's presale, including market volatility, regulatory challenges, and the importance of due diligence.
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Ahead of Monad Crypto Launch, Expert Warns of Worst-Case Scenario  Cryptonews
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Acquiring insight into the future value of XRPUSD is crucial for investors navigating the unpredictable waters of cryptocurrency. Recent forecasts for XRP hover between conservative predictions of £16 by 2030 to exceedingly daring estimates of £800, rising to heights of nearly £3,850. Intense interest stems from expected institutional adoption and Ripple’s ongoing legal dramas. Currently priced at £1.58, XRPUSD is facing a daily dip of 2.3%. As we explore XRP’s potential, we’ll unpack key market indicators and expert opinions.
When discussing XRP price prediction, analysts provide a wide scope of possibilities. Conservative estimates suggest XRP could reach £16 by 2030, a figure driven largely by Ripple’s firm position in cross-border payment solutions. More optimistic forecasts see the cryptocurrency reaching between £800 and nearly £3,850. Such bullish predictions are fueled by a potential increase in institutional adoption and expected regulatory clarity.
Ripple’s ongoing legal battle against the U.S. Securities and Exchange Commission (SEC) is a significant factor. A favorable outcome could unlock new growth pathways for XRP. Regardless of the eventual legal ruling, Ripple continues to secure partnerships that strengthen its ecosystem, further boosting long-term investor confidence.
A closer look at XRPUSD’s technical indicators reveals a challenging environment. The Relative Strength Index (RSI) stands at 33.77, suggesting oversold conditions. However, an ADX of 36.77 indicates a strong trend presence, despite negative momentum seen through a MACD of -0.14.
Bollinger Bands show price volatility, with the current rate near its lower band. The Awesome Oscillator reflects a bearish short-term outlook. Nevertheless, a growing market interest, marked by an MFI of 22.62, hints at potential shifts. Investors should consider these aspects carefully when evaluating their positions.
Institutional adoption plays a crucial role in XRP’s trajectory. Ripple’s strategic alliances with financial institutions continue to bring credibility and new operational use cases to XRP.
The resolution of Ripple’s legal challenges could be pivotal. If Ripple successfully defends against SEC charges, it may bolster XRP, potentially leading to significant price appreciation. Whether these positive developments will materialize remains speculative, but their impact on XRP’s value is undeniable. This anticipation keeps investor interest intact, aligning with the evident growth in XRPUSD’s long-term potential.
Here’s a closer look at potential future scenarios for XRP in 2030.
The future of XRPUSD involves a complex interplay of legal, industry, and market forces. Predicted values ranging from £16 to over £3,850 demonstrate the wide spectrum of possibilities. Institutional uptake and the pending legal resolution are two critical facets that could drive substantial changes in XRP’s value.
For investors, it’s vital to monitor these developments attentively. Each passing event shapes the market’s predictions and the cryptocurrency landscape as a whole. As always, conducting detailed analysis and staying informed will be key to navigating these waters effectively.
Meyka, an AI-driven platform, offers real-time financial insights and predictive analytics to assist investors in making informed decisions amidst such volatility.
As of now, XRPUSD trades at £1.58. It experienced a daily decline of 2.3% but remains up 295% year-over-year, reflecting significant volatility and growth potential.
Ripple’s legal battles with the SEC significantly influence XRP’s price. A positive ruling could unlock new growth opportunities, while a negative outcome might hinder its market expansion.
Long-term predictions for XRP vary widely, from £16 to upwards of £3,850 by 2030. These estimates account for potential institutional adoption and legal outcomes affecting its usage and demand.
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Wintermute is a leading algorithmic trading firm and market maker in the cryptocurrency space. Renowned for providing liquidity across over 50 exchanges and trading platforms, Wintermute plays a pivotal role in ensuring efficient trading and price stability in the volatile crypto market. This article explores Wintermute's activities, its impact on the broader market, and emerging trends shaping the future of decentralized finance (DeFi).
Wintermute's on-chain activity highlights its strategic approach to navigating the evolving crypto landscape. The firm has demonstrated a keen ability to adapt to market conditions, particularly in its interactions with centralized exchanges (CEXs). Following major events like the FTX collapse, Wintermute has adjusted its trading strategies to mitigate risks and maintain liquidity.
Since early 2023, Wintermute's trading activity with major CEXs, including Binance, Coinbase, Kraken, and OKX, has experienced a noticeable decline. Binance remains Wintermute's most utilized CEX, but trading flows have reduced significantly since May 2023. This trend aligns with a broader market-wide decline in trading volumes, driven by increasing regulatory scrutiny and waning investor confidence.
Key events such as the FTX collapse and the LUNA crash have profoundly influenced Wintermute's trading strategies. For instance, during the $19 billion crypto liquidation event in 2025, Wintermute temporarily paused trading to reassess its risk exposure. These actions underscore the firm's rules-based approach to trading and its commitment to mitigating risks during periods of extreme market volatility.
One of the most debated aspects of Wintermute's operations is its use of the 'loan option model.' This practice involves tokens being loaned to market makers, which can sometimes lead to price manipulation and token dumps. While this model provides liquidity, it has also sparked significant controversy within the crypto community.
The 'loan option model' has raised ethical and regulatory concerns. Critics argue that it disproportionately benefits market makers at the expense of smaller crypto projects, often resulting in sharp token price crashes. As regulatory bodies increasingly scrutinize such practices, the crypto industry may see significant changes in market-making operations. These developments could reshape the balance between liquidity provision and ethical trading practices.
Wintermute has demonstrated its adaptability by diversifying into decentralized platforms, showcasing its commitment to innovation within the DeFi ecosystem. This strategic shift highlights the firm's forward-thinking approach to staying relevant in a rapidly evolving market.
One notable example of Wintermute's diversification is its involvement in OutcomeMarket, a decentralized prediction market focused on events like the 2024 U.S. presidential election. This venture underscores Wintermute's interest in exploring new opportunities within the DeFi space, further solidifying its position as a market leader.
Wintermute has also ventured into operating dark automated market makers (AMMs), such as Tessera V. These dark AMMs prioritize trade execution over transparency, offering traders improved liquidity management. This innovation reflects a growing demand for advanced DeFi tools and highlights the shifting priorities of traders seeking better execution in a competitive market.
Wintermute's strategic decisions and trading patterns have far-reaching implications for the broader crypto market. As a major liquidity provider, any changes in its activity can influence market dynamics, including price stability and trading volumes. Additionally, its cautious approach to avoiding insolvent exchanges underscores the importance of risk management in the volatile crypto landscape.
Despite facing criticism for certain practices, Wintermute has also demonstrated the potential for ethical market-making. Successful projects that have benefited from Wintermute's support highlight the possibility of fostering a healthier and more sustainable crypto ecosystem. These case studies serve as a blueprint for balancing liquidity provision with ethical considerations.
Wintermute continues to play a pivotal role as a market maker and liquidity provider in the cryptocurrency industry. From its controversial 'loan option model' to its innovative ventures into decentralized platforms like OutcomeMarket and Tessera V, the firm remains at the forefront of the crypto market's transformation. As the industry matures, Wintermute's strategies and practices will likely shape the future of trading and liquidity in both centralized and decentralized ecosystems.

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Crypto Prices Today: Bitcoin Price Up 1.80% at $92,810, Solana Jumps 3.98% Despite Altcoin Losses  Analytics Insight
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MSCI delisting shock erases 45% of crypto-treasury value  TheStreet
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A preclinical study in test tubes showed that selected plant-based herbal medicines, especially Ghanaian quinine and Japanese knotweed, work better than antibiotics. Image: Shutterstock.
— by Mischa Dykstra
Lyme disease, also called borreliosis, is the most common vector-borne disease in the Northern hemisphere. It is caused by the spirochete (corkscrew-shaped) bacterium Borrelia burgdorferi and close relatives and mainly spread through the bite of infected ticks.
Currently, more than 300,000 new cases are reported in the USA each year, compared to 65,000 in Europe, and these numbers are rising due to climate change and urban sprawl. The standard of care for Lyme disease, a course of antibiotics over 2-4 weeks, is not always effective: at least 10-20% of treated patients continue to experience symptoms after treatment. Late-stage Lyme patients may experience many different symptoms, including fatigue, joint pains, memory problems, facial paralysis, aches, stiffness in the neck, heart palpitations, and severe headaches. The discovery of novel treatments against Lyme disease is therefore of great interest.
Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi► Read original article► Download original article (pdf)
In a new study published in Frontiers in Medicine, researchers from the Johns Hopkins Bloomberg School of Public Health, with colleagues at the California Center for Functional Medicine and Focus Health, surveyed the power of 14 plant-based extracts to kill Borrelia burgdorferi, compared to the currently used Lyme antibiotics doxycycline and cefuroxime.
The researchers tested these extracts’ effectiveness in vitro (outside of a living organism) against the free-swimming "planktonic" form of the bacterium as well as against microcolonies. Microcolonies are aggregates of bacteria, the first stage in the development of biofilms – structured bacterial communities that stick to a surface and are embedded in a slimy extracellular matrix.
The researchers show that plant extracts from black walnut, cat's claw, sweet wormwood, Mediterranean rockrose, and Chinese skullcap had strong activity against B. burgdorferi, outperforming both tested antibiotics.
But by far the strongest performers were Ghanaian quinine (Cryptolepis sanguinolenta; also known as yellow-dye root, nibima, or kadze) and Japanese knotweed (Polygonum cuspidatum).
Ghanaian quinine is a shrub from West Africa containing the antimicrobial alkaloid cryptolepine, and is used in ethnomedicine to treat malaria, hepatitis, septicemia, and tuberculosis. Japanese knotweed is a traditional medicine in India and China that contains the polyphenol resveratrol. In other preclinical studies it has been found to have anti-tumor and anti-inflammatory effects and protect the nervous system and heart. Extracts from both plants were found to kill microcolonies of Borrelia burgdorferi and inhibit division of the planktonic form, even at low concentrations (0.03-0.5%). Remarkably, a single 7-day treatment with 1% Ghanaian quinine could completely eradicate the bacterium – it did not regrow, even under optimal conditions in the drug's absence.
“This study provides the first convincing evidence that some of the herbs used by patients such as Cryptolepis, black walnut, sweet wormwood, cat's claw, and Japanese knotweed have potent activity against Lyme disease bacteria, especially the dormant persister forms, which are not killed by the current Lyme antibiotics,” says Dr Ying Zhang from the Johns Hopkins Bloomberg School of Public Health.
Related: An innovative new diagnostic for Lyme disease
“These findings are exciting as they offer opportunities for improved treatment of persistent Lyme disease, which is not helped by the current standard treatment. We are interested in further evaluating these potent herbal medicines through animal studies as well as clinical trials.”
However, not all tested compounds or herbs yielded positive results against the bacterium. Extracts of grapefruit seeds, green chiretta, ashwagandha, candy leaf (also known as stevia), fuller's teasel, and Japanese teasel had little or no effect_,_ and neither did the chemicals colloidal silver, monoglyceride monolaurin, or antimicrobial peptide LL37 from human immune cells. This was surprising, as anecdotal and preclinical studies suggested that they might be effective, and they are often used in the community of Lyme disease practitioners and patients.
“Many thousands of Lyme patients today, especially those with later-stage symptoms who have not been effectively treated, are in great need of efficacious, accessible treatment options,” says Dr Sunjya K. Schweig, CEO and co-Director of the California Center for Functional Medicine and Scientific Advisory Board Member of the Bay Area Lyme Foundation.
Coauthor Jacob Leone of the FOCUS Health Group stresses: “Patients and their clinicians are increasingly turning to herbal remedies as additional treatment options, and we hope that these findings will help point the way toward a greater understanding of these therapies. But further preclinical studies and clinical trials will be required to establish evidence for effective treatment of Lyme disease patients.”
This research was supported by the Bay Area Lyme Foundation and the Steven & Alexandra Cohen Foundation.
Original article: Evaluation of Natural and Botanical Medicines for Activity against Growing and Non-growing Forms of B. burgdorferi
February 21, 2020
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